Yayın tarihi için European Journal of Life Sciences listeleme
Toplam kayıt 41, listelenen: 1-20
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Design, synthesis and in vitro COX inhibitory profiles of a new series of tetrazole-based hydrazones
(Anadolu Üniversitesi, 2022)Inhibition of cyclooxygenases (COXs), by selective and nonselective inhibitors, is a favorable approach for pharmacologic intervention in a variety of disorders such as cancer. For this purpose, a new class of tetrazole-hydrazone ... -
Synthesis and characterization of new piperazinedithiocarbamate compounds as potent MAO-A inhibitors
(Anadolu Üniversitesi, 2022)Monoamine oxidase (MAO) enzymes have an important place in neurodegenerative diseases. While MAO-A inhibitors are used in depression; MAO-B enzyme has an important place in Parkinson's disease. Within the scope of this ... -
High-density lipoprotein: Quality is more important than quantity!
(Anadolu Üniversitesi, 2022)High density lipoproteins (HDLs) are complex lipid carriers which replace their own structures and functions according to different conditions including healthy or pathological status. HDL has substantial roles in reverse ... -
Chaerophyllum libanoticum Boiss. Et Kotschy: The fruit essential oil, composition, skin-whitening and antioxidant activities
(Anadolu Üniversitesi, 2022)This study was aimed to evaluate the essential oil composition of Chaerophyllum libanoticum fruits and its potential uses in the cosmetic industry. The essential oil was analyzed by Gas Chromatography (GC) and Gas ... -
Synthesis and in silico evaluation of some new 2,4-disubstituted thiazole derivatives
(Anadolu Üniversitesi, 2022)The synthesis and anti-proliferative activity investigation of methyl 3/4-[[4-(2-substituted thiazol-4-yl)phenyl]amino]-3-oxopropanoate/(4-oxobutanoate) (3a-h) derivatives were aimed in this work. The synthesis of the new ... -
Volatile compositions of Tilia platyphyllos Scop. infusions by headspace-solid-phase microextraction (HS-SPME), antioxidant activity
(Anadolu Üniversitesi, 2022)The genus Tilia (Tiliaceae) represents 45 species, of which six species are European. Tilia sp. are simple, cordate or deciduous trees with long, silicate shaped, 5-valve fruits and fragrant flowers. It is used as a medicinal ... -
Arum italicum Miller tuber extracts: Evaluation of synergistic activities with ciprofloxacin against some pathogens
(Anadolu Üniversitesi, 2022)Antibiotic misuse or overuse leads antibiotic resistance. Antibiotic resistant bacteria infections cause significant clinical problem. Recently, antibiotic resistant bacteria numbers have increased, this situation has ... -
Essential oil composition and antimicrobial activity of Glaucosciadium cordifolium (Boiss.) Burtt. & Davis
(Anadolu Üniversitesi, 2022)Glaucosciadium cordifolium (Boiss.) Burtt. & Davis, which is a monotypic species naturally grown in Turkey belonging to the Apiaceae (Umbelliferae) family. In this study, the essential oil obtained from G. cordifolium was ... -
Focusing on the moderately active compound (MAC) in the design and development of strategies to optimize the apoptotic effect by molecular mechanics techniques
(Anadolu Üniversitesi, 2022)Today, chemotherapeutic agents are mostly used to fight cancer in clinics. But even though they have selectivity for cancer cells, their mechanism of action could result in necrosis. Therefore, we aimed to suggest new ... -
Latest research about active pharmaceutical ingredient loaded Poly Lactic Acid-co-Glycolic Acid (PLGA) based drug delivery system in Türkiye
(Anadolu Üniversitesi, 2022)Some of the most well-engineered and produced biomaterials are polyesters based on polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers, polylactic acid co-glycolic acid (PLGA). In controlled release systems, ... -
Release kinetics of 3D printed oral solid dosage forms: An overview
(Anadolu Üniversitesi, 2022)Three-dimensional printing (3DP) is one of the most extensively researched methods for producing nano/micro scale biomaterials. This method is typically applied layer by layer. The 3DP method has many advantages over ... -
Geographical impact on essential oil composition of endemic Salvia absconditiflora collected from different parts of Turkey
(Anadolu Üniversitesi, 2022)This study was carried out to determine the content of the essential oils of Salvia absconditiflora Greuter & Burdet populations which are naturally found in Mediterranean, Iran-Turan and Euro-Sibirya phytogeographical ... -
Morpho-anatomical and palynological properties of endemic Astragalus tmoleus var. bounacanthus (Fabaceae)
(Anadolu Üniversitesi, 2022)Astragalus tmoleus Boiss. var. bounacanthus (Boiss.) Chamberlain is a member of the Pterophorus Bunge section of the Fabaceae family and consists of the spiny cushion-forming shrub. In this study, morphological, anatomical ... -
Antimicrobial and antioxidant activities of Sideritis lanata L. extracts
(Anadolu Üniversitesi, 2022)Sideritis L. (Lamiaceae) is represented by 45 species in Flora of Turkey. Sideritis lanata L. (Hairy ironwort) is located in the north-west, west, south-west and central Anatolia. Mountain tea (Sideritis plants) is used ... -
Capsaicin inhibits proliferation and induces apoptosis in human lung adenocarcinoma A549 cell line
(Anadolu Üniversitesi, 2022)Capsaicin is the main component of many hot peppers, exerts anticancer effects on various cancer cells by inducing apoptotic pathways. In addition, the ineffectiveness of this apoptotic effect of capsaicin on healthy cells ... -
Oral medicine administration errors in a patient with an enteral feeding tube
(Anadolu Üniversitesi, 2023)Proper nutrition is vital for all patients with an expected lifespan. It is strongly recommended that patients whose oral intake is impaired or suspected to be impaired should be provided nutritional support. Concurrent ... -
A new HPLC method for selexipag analysis in pharmaceutical formulation and bulk form
(Anadolu Üniversitesi, 2023)Selexipag is a new non-prostanoid prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Selexipag is a long-acting IP receptor agonist with a shorter half-life than all other licensed drugs targeting ... -
Evaluation of in vitro hepatotoxicity of perampanel in comparison with carbamazepine: old versus new
(Anadolu Üniversitesi, 2023)Since the liver metabolizes many drugs, including antiepileptics, this organ is the main target of drug-induced damage. There is very little data on hepatotoxicity due to carbamazepine and perampanel metabolized in the ... -
Screening of new morpholine dithiocarbamate derivatives bearing benzimidazole moiety for anticholinesterase potential
(Anadolu Üniversitesi, 2023)Alzheimer’s disease (AD) is basically associated with disturbances of cholinesterase metabolism which result in acetylcholine deficiency. Target of acetylcholinesterase (AChE) inhibitors used in symptomatic therapy of ... -
Etiopathogenesis of depression and experimental depression models used in preclinical studies
(Anadolu Üniversitesi, 2023)Depression is the most frequent psychiatric illness among mood disorders, affecting approximately 10% of adults. Especially recurrent and moderate/severe depression can become a serious public health problem by impairing ...
