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Design, synthesis and in vitro COX inhibitory profiles of a new series of tetrazole-based hydrazones
(Anadolu Üniversitesi, 2022)Inhibition of cyclooxygenases (COXs), by selective and nonselective inhibitors, is a favorable approach for pharmacologic intervention in a variety of disorders such as cancer. For this purpose, a new class of tetrazole-hydrazone ... -
Synthesis and characterization of new piperazinedithiocarbamate compounds as potent MAO-A inhibitors
(Anadolu Üniversitesi, 2022)Monoamine oxidase (MAO) enzymes have an important place in neurodegenerative diseases. While MAO-A inhibitors are used in depression; MAO-B enzyme has an important place in Parkinson's disease. Within the scope of this ... -
High-density lipoprotein: Quality is more important than quantity!
(Anadolu Üniversitesi, 2022)High density lipoproteins (HDLs) are complex lipid carriers which replace their own structures and functions according to different conditions including healthy or pathological status. HDL has substantial roles in reverse ... -
Chaerophyllum libanoticum Boiss. Et Kotschy: The fruit essential oil, composition, skin-whitening and antioxidant activities
(Anadolu Üniversitesi, 2022)This study was aimed to evaluate the essential oil composition of Chaerophyllum libanoticum fruits and its potential uses in the cosmetic industry. The essential oil was analyzed by Gas Chromatography (GC) and Gas ... -
Synthesis and in silico evaluation of some new 2,4-disubstituted thiazole derivatives
(Anadolu Üniversitesi, 2022)The synthesis and anti-proliferative activity investigation of methyl 3/4-[[4-(2-substituted thiazol-4-yl)phenyl]amino]-3-oxopropanoate/(4-oxobutanoate) (3a-h) derivatives were aimed in this work. The synthesis of the new ...
