Yazar "Akalın Çiftçi, Gülsen" için listeleme
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Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl) phenyl]acetamide derivatives and evaluation of their anticancer activity
Özkay, Yusuf; Işıkdağ, İlhan; Seller, Zerrin; Akalın Çiftçi, Gülsen (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)In the present study 18 novel imidazole-(benz)azole and imidazole-piperazine derivatives were synthesized in order to investigate their probable anticancer activity. The structures of the compounds were confirmed by IR, ... -
Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Özdemir, Ahmet; Turan, Gülhan; İşcan, Gökalp; Akalın Çiftçi, Gülsen; Abu Mohsen, Usama (Taylor & Francis LTD, 2014)In this study, 14 different 2-[(1-methyl-1H-tetrazole-5-yl)thio]-1-(phenyl) ethanone derivatives (1-14) were synthesized. The structures of the obtained compounds were elucidated using IR, H-1-NMR, C-13-NMR and FAB(+)-MS ... -
Synthesis, antimicrobial activity and cytotoxicity of novel oxadiazole derivatives
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Turan, Gülhan; Özdemir, Ahmet; Öziç, Rasime; Akalın Çiftçi, Gülsen (Taylor & Francis LTD, 2012)In the present study, 5-substituted-1,3,4-oxadiazolin-2-thiones (1a-b) were synthesized via the ring closure reactions of appropriate acid hydrazides with carbon disulphide. N-(Benzothiazol-2-yl)-2-[[5-substituted-1,3,4- ... -
Synthesis, characterization of some transition-metal complexes of a new heptadentate N(5)S(2) Schiff-base ligand and the effects of these metal complexes on U2OS cells cytotoxicity and DNA cleavage activity
Uluçam, G.; Beynek, Nesrin; Seller, Zerrin; Akalın Çiftçi, Gülsen; Turan, Gülhan; Benkli, Kadriye (Taylor & Francis LTD, 2008)Metal complexes of a heptadentate N(5)S(2) donor Schiff-base ligand were synthesized by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2 '-bipyridine-6,6'-dicarboxaldehyde in the presence of ... -
Towards Novel Anti-tumor Strategies for Hepatic Cancer: epsilon-Viniferin in Combination with Vincristine Displays Pharmacodynamic Synergy at Lower Doses in HepG2 Cells
Özdemir, Filiz; Akalın Çiftçi, Gülsen; Sen, Mesut; Önder, Nur İpek; İşcan, Arzu; Kutlu, Hatice Mehtap; Seller, Zerrin (Mary Ann Liebert, Inc, 2014)Hepatocellular carcinoma is the fifth most common cancer and the third leading cause of cancer-related deaths worldwide. The efficacy of novel combination treatments are increasingly evaluated with use of integrative biology ...