Yazar "Şenel, Behiye" için listeleme
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Development of paclitaxel-loaded liposomal systems with anti-her2 antibody for targeted therapy
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Gezgin, Seval (Pharmacotherapy Group, 2016)Purpose: To develop liposome formulations containing monoclonal antibody anti-HER2 (MabHer2), and Paclitaxel (PTX). Methods: Seven different liposomal systems containing PTX, or MabHer2 or a combination of PTX and MabHer2 ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
Anadolu Üniversitesi, Eczacılık Fakültesi; 0000-0001-9596-0538; 0000-0002-7979-0089; 0000-0002-8041-6844; 0000-0001-9747-8307; 0000-0002-7492-1668; Öztürk, A. Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Dexketoprofen Trometamol-Loaded Kollidon (R) SR and Eudragit (R) RS 100 Polymeric Nanoparticles: Formulation and In Vitro-In Vivo Evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon (R) SR (KSR) and Eudragit (R) RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Effects of different derivatives of eudragit polymer on entrapment efficiency, in vitro dissolution, release kinetics and cell viability results on extended release flurbiprofen loaded nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Engineering Monoclonal Antibodies: Production and Applications
Büyükköroğlu, Gülay; Şenel, Behiye (Academic Press LTD-Elsevier Science LTD, 2018)… -
Graphene quantum dots: Synthesis, characterization, cell viability, genotoxicity for biomedical applications
Şenel, Behiye; Demir, Neslihan; Büyükköroğlu, Gülay; Yıldız, Mustafa (Elsevier, 2019)We report the synthesis and applications of a novel N-doped graphene quantum dots (GQDs) using hydrothermal reaction between citric acid and p-aminophenol. The synthesized N-doped GQDs have been characterized physico-chemically ... -
In vitro preliminary studies of chitooligosaccharide coated nanostructured lipidic nanoparticles for efficient gene delivery
Şenel, Behiye (Marmara University, 2019)Gene therapy is generally defined as the transfer of genetic material to cells to treat a disease or at least improve the clinical condition of a patient. The most commonly used vectors in gene therapy are viral and non-viral ... -
Ornidazole Incorporated Chitosan Nanoparticles for Ocular Application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Ornidazole incorporated chitosan nanoparticles for ocular application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Preparation and evaluation of carvedilol-loaded solid lipid nanoparticles for targeted drug delivery
Kipriye, Zeynep; Şenel, Behiye; Yenilmez, Evrim (Pharmacotherapy Group, 2017)Purpose: To develop suitable solid lipid nanoparticles (SLN) containing carvedilol (CL) for controlled delivery to site of action. Methods: Solid lipid nanoparticles (SLNs) containing carvedilol (CL) were prepared by hot ... -
Preparation and In Vitro Evaluation of DNA-Bonded Polymeric Nanoparticles as New Approach for Transcutaneous Vaccination
Büyükköroğlu, Gülay; Şenel, Behiye; Karabacak, Rukiye B. (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ... -
Preparation and in vitro evaluation of DNA-bonded polymeric nanoparticles as new approach for transcutaneous vaccination
Büyükköroğlu, Gülay; Şenel, Behiye; Karabacak, Rukiye B. (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ... -
Preparation and in vitro evaluation of vaginal formulations including siRNA and paclitaxel-loaded SLNs for cervical cancer
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Yenilmez, Evrim; Yazan, Yasemin (Elsevier Science BV, 2016)Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic ... -
Preparation, Characterization and In Vitro Evaluation of Dirithromycin Loaded Eudragit (R) RS 100 Nanoparticles for Topical Application
Yenilmez, Evrim; Kırımlıoğlu, Gülsel Yurtdaş; Şenel, Behiye; Başaran, Ebru (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The purpose of the study was to formulate dirithromycin (DR) loaded Eudragit (R) RS 100 (ERS) nanoparticles for topical application and to analyze the physical and chemical characteristics and in vitro toxicity of the ... -
The simultaneous delivery of paclitaxel and Herceptin (R) using solid lipid nanoparticles: In vitro evaluation
Büyükköroğlu, Gülay; Şenel, Behiye; Gezgin, Seval; Tan Dinh (Elsevier Science BV, 2016)This study was aimed at formulating Paclitaxel (R)-loaded solid lipid nanoparticles (SLN) complexed with Herceptin (R). The physicochemical characterizations of the SLNs/Herceptin (R) complexes such as particle size and ... -
SiRNA taşıyıcı sistem geliştirme ve değerlendirme çalışmaları
Şenel, Behiye (Anadolu Üniversitesi, 2013)Kontrolsüz hücre çoğalması, kitle veya tümör oluşumu ile karakterize olan kanser günümüzün en önemli sağlık sorunlarından birisidir. Kontrolsüz gerçekleşen çoğalma, DNA’da meydana gelen mutasyonlar sonucu (onkojen aktivasyonu, ... -
Vaginal suppositories with siRNA and paclitaxel-incorporated solid lipid nanoparticles for cervical cancer: Preparation and in vitro evaluation
Büyükköroğlu, Gülay; Şenel, Behiye; Yenilmez, Evrim (Humana Press Inc., 2019)The objective of this study is to prepare vaginal suppository containing chemotherapeutic agent and genetic material that can be applied locally for cervical cancer. Cervical cancer is one of the most life-threatening types ...
