WoS İndeksli Yayınlar Koleksiyonu by Institution Author "Sever, Belgin"
Now showing items 21-26 of 26
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Synthesis and Evaluation of New Benzodioxole-Based Thiosemicarbazone Derivatives as Potential Antitumor Agents
Altıntop, Mehlika Dilek; Temel, Halide Edip; Sever, Belgin; Çiftçi, Gülsen Akalın; Kaplancıklı, Zafer Asım (MDPI, 2016)New benzodioxole-based thiosemicarbazone derivatives were synthesized and evaluated for their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma and NIH/3T3 mouse embryonic fibroblast cells. In order to ... -
Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9
Özdemir, Ahmet; Sever, Belgin; Altıntop, Mehlika Dilek; Temel, Halide Edip; Atlı Eklioğlu, Özlem; Baysal, Merve; Demirci, Fatih (MDPI, 2017)Matrix metalloproteinases (MMPs) are important proteases involved in tumor progression including angiogenesis, tissue invasion, and migration. Therefore, MMPs have been reported as potential diagnostic and prognostic ... -
Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
Kaplancıklı, Zafer Asım; Sever, Belgin; Altıntop, Mehlika Dilek; Atlı Eklioğlu, Özlem; Baysal, Merve; Özdemir, Ahmet (Bentham Science Publ LTD, 2017)Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have attracted a great deal of interest due to their pivotal role in the field of current cancer research. Methods: In the present study, ... -
Synthesis and Evaluation of Tetrazole-Based Hydrazone Derivatives Bearing a Pyridine Moiety as Antimicrobial Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Sever, Belgin; Cantürk, Zerrin; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2015)2-[(1-Methyl/Phenyl-1H-tetrazol-5-yl)thio]-N'-[(aryl) methylidene/ethylidene] acetohydrazides were synthesized and investigated in vitro against pathogenic bacteria and Candida species for their antimicrobial activity using ... -
Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Sever, Belgin; Cantürk, Zerrin; Özdemir, Ahmet (Hindawi LTD, 2016)In an effort to develop potent antimicrobial agents, new thiosemicarbazone derivatives were synthesized via the reaction of 4-[4-(trifluoromethyl)phenyl]thiosemicarbazide with aromatic aldehydes. The compounds were evaluated ... -
Synthesis of New Thiazolyl-pyrazoline Derivatives and Evaluation of Their Antimicrobial, Cytotoxic and Genotoxic Effects
Sever, Belgin; Altıntop, Mehlika Dilek; Karaca Gencer, Hülya; Kapkac, Handan Acelya; Atlı Eklioğlu, Özlem; Baysal, Merve; Özdemir, Ahmet (Bentham Science Publ LTD, 2018)Background: Pyrazolines have played a pivotal role in antimicrobial and anticancer drug discovery. Moreover, thiazoles have attracted a great deal of interest due to their crucial roles in the lead identification and ...