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Toplam kayıt 14, listelenen: 1-10
Comparing the Role of Silymarin on Survival Rate of Rat Glioma With Primary Mixed Rat Glia Cells in Vitro
(Parlar Scientific Publications (PSP), 2013)
Phytochemicals, nutraceuticals and herbal products, such as silymarin, have gained ever growing popularity and are valued for their ability to defend against almost all types of disease. Primarily known as hepatoprotective ...
Thymoquinone Inhibits the Proliferation and Induces Apoptosis of Cancer Cells in Vitro
(Wiley-Blackwell, 2015)
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Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis
(Informa Healthcare, 2014)
Dual inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX) pathways of arachidonic acid metabolism prevent cancer development and induce apoptosis. One of the most promising compounds that blocks both of these pathways ...
The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro
(Springer, 2018)
Ceramide is found to be involved in inhibition of cell division and induction of apoptosis in certain tumour cells. Ceranib-2 is an agent that increases ceramide levels by inhibiting ceramidase in cancer cells. Therefore, ...
The role of hemostatic mechanisms in the development of thrombosis in Behcet's disease: an analysis by modified rotation thromboelastogram (ROTEM)
(Springer London LTD, 2013)
Behcet's disease (BD) is a multisystemic disorder characterised by recurrent oral and genital ulcers. Vasculitis and thrombotic events are the most important causes of mortality. Thrombosis is the major clinical finding ...
Erythropoietin Protects the Kidney by Regulating the Effect of TNF-alpha in L-NAME-Induced Hypertensive Rats
(Karger, 2018)
Background/Aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-alpha plays a major role in inflammation and also depresses the synthesis ...
Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2
(Springer, 2015)
Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study investigates the potential ...
Effects of ceranib-2 on cell survival and TNF-alpha in colon cancer cell line
(Comenius University, 2017)
OBJECTIVE: The aim of this study was to investigate the effects of a novel anti-cancer drug, ceranib-2, which targets the acid ceramidase, in human colon cancer cell line. MATERIALS AND METHODS: The cell lines were treated ...
Antiproliferative and antiapoptotic effect of thymoquinone on cancer cells in vitro
(Comenius University, 2018)
OBJECTIVES: Nigella sativa oil and thymoquinone were comparatively tested in vitro for their effects on human cancer cell lines (glioma, T98; prostate, LnCaP) as well as mouse embryonic fi broblast cell lines (3T3), and ...
Comparative Study on Induction of Apoptosis in A549 Human Lung Adenocarcinoma Cells by C2 Ceramide or Ceranib-2
(Zoological Soc Pakistan, 2017)
Investigation of ceramide and ceramidases on cancer therapy had become popular in recent years. Ceramide is a metabolite in sphingolipid pathway of the cells that has an ability to promote cell death in tumor cells when ...