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Toplam kayıt 24, listelenen: 1-10
Serum Thrombopoietin Levels and Its Relationship With Thrombocytopenia in Patients With Cirrhosis
(Kowsar Publ, 2014)
Background: Patients with cirrhosis usually have thrombocytopenia in discrete levels. The mechanism of thrombocytopenia is thought as splenic sequestration and destruction of platelets, impaired bone marrow generation and ...
Akut ve Kronik Sigara İçen Genç Bireylerde Proinflamatuar Durumda HDL Fonksiyonlarının Önemi Nedir?
(2017)
Amaç: Sigara içimi, kardiyovasküler hastalıkların en önemli ve önlenebilir risk faktörlerinden biridir. Okside LDL, kardiyovasküler hastalıklarda artış gösterir. Normal yüksek dansiteli lipoprotein (HDL), LDL'yi oksidasyondan ...
Antioxidant and Antiradical Properties of Selected Flavonoids and Phenolic Compounds
(Hindawi LTD, 2017)
Phenolic compounds and flavonoids are known by their antioxidant properties and one of the most important sources for humans is the diet. Due to the harmful effects of synthetic antioxidants such as BHA and BHT, natural ...
Evaluation of Inhibition Effects of Some Cardiovascular Therapeutics on Human Erythrocyte Carbonic Anhydrase Isoenzymes
(2018)
Carbonic anhydrase enzyme plays a vital role in metabolic events such as acid-base regulation and respiration. In our research, it is tried to determine the inhibitory influences of the cardiovascular therapeutics esmolol ...
The effects of atorvastatin on antioxidant/antiinfammatory properties of HDLs in hypercholesterolemics
(2015)
Background/aim: Hypercholesterolemia is characterized by changes in lipid profle, nitric oxide pathway, and oxidative stress markers, but functions of high-density lipoprotein (HDL) were not well established in ...
Direct and protective effects of single or combined addition of vincristine and epsilon-viniferin on human HepG2 cellular oxidative stress markers in vitro
(Springer, 2016)
The objective of this study is to examine the direct effects of low doses and high doses of epsilon-viniferin, a substance known to be an antioxidant, and vincristine sulphate, a chemotherapeutic agent, alone and in ...
Phytase from Weissella halotolerans: purification, partial characterisation and the effect of some metals
(Taylor & Francis Inc, 2017)
In the study, phytase was purified in three simple steps comprising ammonium sulphate precipitation, anion exchange and gel filtration chromatography from Weissella halotolerans. The enzyme was obtained with a specific ...
Towards Novel Anti-tumor Strategies for Hepatic Cancer: epsilon-Viniferin in Combination with Vincristine Displays Pharmacodynamic Synergy at Lower Doses in HepG2 Cells
(Mary Ann Liebert, Inc, 2014)
Hepatocellular carcinoma is the fifth most common cancer and the third leading cause of cancer-related deaths worldwide. The efficacy of novel combination treatments are increasingly evaluated with use of integrative biology ...
Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study
(Taylor & Francis LTD, 2017)
Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 ...
Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors
(Turkish Pharmacists Assoc, 2018)
Objectives: In recent years, the design of anticholinesterase agents based on molecular hybridization of pharmacologically active scaffolds has attracted a great deal of interest in medicinal chemistry. For this purpose, ...