Ara
Toplam kayıt 10, listelenen: 1-10
Preparation and in vitro evaluation of DNA-bonded polymeric nanoparticles as new approach for transcutaneous vaccination
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)
The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ...
Preparation and In Vitro Evaluation of DNA-Bonded Polymeric Nanoparticles as New Approach for Transcutaneous Vaccination
(Colegio Farmaceuticos Provincia De Buenos Aires, 2017)
The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ...
Development of Solid Lipid Gene Delivery System
(2016)
Rekombinant DNA teknolojisindeki ilerlemelerin doğal sonucu olarak, kalıtsal hastalıkların iyileştirilmesi için gen tedavisi gündeme gelmiştir. Gen tedavisinde amaç, vücuttan alınan hücreler içinde yeni genetik materyalin ...
Development of solid lipid gene delivery system [Katı lipit gen taşıyıcı sistem geliştirilmesi]
(Turkish Pharmacists Association, 2016)
As a natural result of the progresses made in the recombinant DNA technology, the gene treatment has been brought forward for the improvement of genetic disorders. The purpose of the gene therapy is the treatment of the ...
Preparation and in vitro evaluation of vaginal formulations including siRNA and paclitaxel-loaded SLNs for cervical cancer
(Elsevier Science BV, 2016)
Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic ...
The simultaneous delivery of paclitaxel and Herceptin (R) using solid lipid nanoparticles: In vitro evaluation
(Elsevier Science BV, 2016)
This study was aimed at formulating Paclitaxel (R)-loaded solid lipid nanoparticles (SLN) complexed with Herceptin (R). The physicochemical characterizations of the SLNs/Herceptin (R) complexes such as particle size and ...
Development of paclitaxel-loaded liposomal systems with anti-her2 antibody for targeted therapy
(Pharmacotherapy Group, 2016)
Purpose: To develop liposome formulations containing monoclonal antibody anti-HER2 (MabHer2), and Paclitaxel (PTX). Methods: Seven different liposomal systems containing PTX, or MabHer2 or a combination of PTX and MabHer2 ...
Preparation and physicochemical characterizations of solid lipid nanoparticles containing DOTAP for DNA delivery
(Scientific Technical Research Council Turkey-Tubitak, 2015)
The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ...
Preparation and physicochemical characterizations of solid lipid nanoparticles containing DOTAP?R for DNA delivery
(2015)
The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ...
Graphene quantum dots: Synthesis, characterization, cell viability, genotoxicity for biomedical applications
(Elsevier, 2019)
We report the synthesis and applications of a novel N-doped graphene quantum dots (GQDs) using hydrothermal reaction between citric acid and p-aminophenol. The synthesized N-doped GQDs have been characterized physico-chemically ...