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Toplam kayıt 308, listelenen: 1-10
Some thiazolylaminopyrrole derivatives and their antimicrobial activity
(1999)
In this study, some ethyl 1-(4-arylthiazol-2-yl)amino-2-methyl-5-aryl-1H-pyrrole-3-carboxylic acid derivatives were obtained by reacting 1-(2-methyl-3-carbethoxy-5-arylpyrrol-1-yl)thioureas with ?-bromoacetophenone ...
Synthesis of Some Benzothiazole Based Piperazine-Dithiocarbamate Derivatives and Evaluation of Their Anticancer Activities
(Bentham Science Publ LTD, 2011)
Some benzothiazole derivatives bearing piperazine and dithiocarbamate moieties were synthesized in order to investigate their anticancer activity. The structures of the obtained compounds were confirmed by spectral data ...
Synthesis and Evaluation of a New Series of Arylidene Indanones as Potential Anticancer Agents
(Bentham Science Publ LTD, 2018)
Background: Arylidene indanones have attracted a great deal of interest due to their outstanding therapeutic applications. In particular, considerable research has pointed out the importance of arylidene indanones in the ...
Synthesis and characterization of new binaphthyl-linked phenanthroline-, bipyridine-, or pyridine-derived ligands, and the study of their cytotoxic activity
(2008)
In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphthyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see ...
In silico Molecular Docking and ADME Studies of 1 3,4-Thiadiazole Derivatives in Relation to in vitro PON1 Activity
(Bentham Science Publ LTD, 2019)
Background: Paraoxonase 1 (PON1) is a paraoxonase, arylesterase and lactonase associated with protection of lipoproteins and cell membranes against oxidative modification. Objective: Based on antioxidative properties of ...
Biological Activity Evaluation of Novel 1,2,4-Triazine Derivatives Containing Thiazole/Benzothiazole Rings
(Bentham Science Publ LTD, 2017)
Background: Triazine ring is a prominent structural motif found in some azanucleosides whose efficiency improved many times in the research area of antitumor agents. Objective: In this study, we have designed and synthesized ...
QSAR of smooth muscle relaxation by 2,5-substituted-benzimidazole derivatives
(1997)
Quantitative structure-activity anlayses were carried out for in vitro relaxant actions of a series of 2,5-substituted-benzimidazoles in rat duodenal smooth muscle. Analyses of simple and multiple linear regression models ...
Synthesis of some 6,7-disubstituted imidazo[4,5-g]quinoxaline derivatives as possible antimicrobials
(1998)
In this study, some 6,7-disustituted imidazo[4,5-g]quinoxaline derivatives were synthesized by reacting 5,6-diaminobenzimidazole and some 1,2-dicarbonyl compounds. The antibacterial and antifungal activities of the compounds ...
Synthesis and Biological Evaluation of some Amide Derivatives Bearing Benzothiazole and Piperidine Moieties as Antimicrobial Agents
(Bentham Science Publ LTD, 2013)
In this study, N-(benzothiazol-2-yl)-2-(piperidin-1-yl)acetamide derivatives (1-24) were obtained by the reaction of 2-chloro-N-(benzothiazole-2-yl)acetamides with piperidine derivatives. The structures of the compounds ...
Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors
(Bentham Science Publ LTD, 2017)
Background: In recent years, the relationship between overexpression of matrix metalloproteinases ( MMPs) and tumor invasion/metastasis has prompted researchers to develop MMP inhibitors as anticancer drugs. Objective: The ...