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Toplam kayıt 56, listelenen: 1-10
Gamma-aminobutyric acid loaded halloysite nanotubes and in vitro-in vivo evaluation for brain delivery
(Elsevier Science BV, 2015)
Gamma-aminobutyric acid (GABA) is a key neurotransmitter where it usually inhibits impulse transmission. GABA release blockage or postsynaptic reaction were determined to provoke epileptic convulsions. The aim of the present ...
Design and Characterization of Montelukast Sodium Loaded Kollidon (R) SR Nanoparticles and Evaluation of Release Kinetics and Cytotoxicity Potential
(Colegio Farmaceuticos Provincia De Buenos Aires, 2019)
The objective of this research was to design and characterize montelukast sodium (MS) loaded novel nanosized and biocompatible Kollidon (R) SR nanoparticles to provide prolonged release behavior that can improve bioavailability, ...
Ornidazole incorporated chitosan nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)
Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ...
Chitosan nanoparticles for ocular delivery of cyclosporine A
(Taylor & Francis LTD, 2014)
In the present study, cyclosporine A (CsA) was successfully incorporated into cationic chitosan nanoparticles by spray-drying method aiming ocular application. Physicochemical characterisation of particles was performed ...
Preparation and characterization of methotrexate-loaded microcapsules
(Taylor & Francis LTD, 2014)
Methotrexate (MTX) has toxic effect to healthy tissues. Microencapsulation coats particles with a functional coat to optimize storage stability and to modulate release. In the present study, a new MTX encapsulated microcapsules ...
Studies on prolonged release matrix tablet formulations of hydralazine hydrochloride
(2003)
The purpose of this study was to prepare prolonged release tablet formulations of hydralazine hydrochloride which has been used as an antihypertensive agent. To achieve this, carbomers (Carbopol® 834, 934, 940 and 1342) ...
The aggregation behavior of trimetazidine hydrochloride in aqueous solutions at different temperatures
(Elsevier Science BV, 2015)
The aggregation behavior of trimetazidine hydrochloride (TMZ HCl) in aqueous solutions has been investigated by electrical conductivity, ultrasonic speed and density measurements in the temperature ranges from 298.15 to ...
Physicochemical characterization and dissolution properties of cinnarizine solid dispersions
(2005)
Sudaki çözünürlüğü düşük olarak bilinen kalsiyum antagonisti sinnarizinin biyoyararlanımı değişken veya düşüktür. Bu özellikteki bir ilaç materyalinin çözünme davranışının iyileştirilmesi, oral biyoyararlanımı geliştirebilir. ...
Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size
(Bentham Science Publ LTD, 2018)
Aims and Objectives: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria ...
Preparation and characterization of polymeric and lipid nanoparticles of pilocarpine HCl for ocular application
(Informa Healthcare, 2013)
Pilocarpine is used topically in the treatment of glaucoma. Various studies were performed to improve the bioavailability and prolong the residence time of drugs in ocular drug delivery. Drug loaded polymeric and lipid ...