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Toplam kayıt 7, listelenen: 1-7
Reproductive toxicity after levetiracetam administration in male rats: Evidence for role of hormonal status and oxidative stress
(Public Library Science, 2017)
Levetiracetam (LEV) is an antiepileptic drug commonly used in the treatment of epilepsy because of its excellent safety profile in all age groups. It is remarkable that there are no studies evaluating the toxic effects of ...
Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms
(Wolters Kluwer Medknow Publications, 2017)
This study was conducted to clarify the toxic effects of sertraline (SRT) on the reproductive system of male rats and to elucidate the underlying mechanisms. Rats were treated orally with SRT at doses of 5, 10, and 20 mg ...
Reproductive toxic effects and possible mechanisms of zonisamide in male rats
(SAGE Publications Ltd, 2019)
Zonisamide (ZNS) is an anticonvulsant which is used to treat the symptoms of epilepsy. Although it is frequently used during reproductive ages, studies that investigated the effects of ZNS on reproductive system are limited. ...
Evidence for cardiotoxicity associated with sertraline in rats
(Royal Soc Chemistry, 2018)
Sertraline is an antidepressant that is frequently prescribed to treat depression, obsessive-compulsive disorder, panic disorder, and anxiety. This drug had a safe cardiotoxicity profile, until the reporting of cases of ...
Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress
(Hindawi LTD, 2018)
Depression and anxiety are recognized as public health problems. Epidemiological studies have shown that depression and anxiety often occur during reproductive ages between 20 and 60 years of age in males. Trazodone is one ...
Citalopram Induces Reproductive Toxicity in Male Rats
(Wiley, 2017)
Background: Citalopram hydrobromide (CTL) has been shown to cause sexual dysfunction; however, its reproductive toxicity potential has not been sufficiently elucidated in men. Therefore, we aimed to clarify the toxic effects ...
Assessment of trazodone-induced cardiotoxicity after repeated doses in rats
(SAGE Publications LTD, 2019)
Trazodone (TRZ) is an antidepressant drug commonly used in the treatment of depression, anxiety, and insomnia. Although some studies demonstrated the adverse effects of TRZ related to cardiovascular system, the conflicting ...