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Toplam kayıt 23, listelenen: 1-10
Investigation of cytogenetic effects of 2, 4, 5 triphenyl imidazole by rat bone marrow micronucleus test
(2001)
The cytogenetic effects of 2, 4, 5 triphenyl imidazole on the micronucleus formation were investigated in rats. Increasing doses of the substance were injected i.p. into Wistar rats and polychromatic and normochromatic ...
The effects of n-ras oncogene expression on PDGF-BB stimulated responses in cultured mouse myoblasts
(1995)
The role of the ras oncogene in the signalling pathway triggered by platelet-derived growth factor BB (PDGF-BB) has been investigated in a cell line which normally differentiates into myotubes. Following the activation of ...
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
(Bmc, 2018)
Background: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective ...
Genotoxicity and antigenotoxicity of Origanum oil and carvacrol evaluated by Ames Salmonella/microsomal test
(Elsevier Sci LTD, 2005)
This study evaluates the genotoxic and antigenotoxic effects of the essential oil of Origanum onites L. and carvacrol that are used in medicine, flavouring of food and crop protection by Ames Salmonella/microsomal test. ...
Stimulation of dendritic cells with vaccine and vaccine-antibody complex and effect on immune response
(Tubitak Scientific & Technical Research Council Turkey, 2013)
Dendritic cell (DC) vaccines are a promising and potent therapeutic tool for chronic diseases, autoimmune diseases, and cancer because of the unique ability of DCs to stimulate T cells. The challenge of DC vaccines is to ...
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
(Pergamon-Elsevier Science LTD, 2013)
Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ...
Biological activities of Cu(II) and Hg(II) complexes of a heptadentate Schiff base ligand
(Tubitak Scientific & Technical Research Council Turkey, 2010)
Two metal complexes were synthesized as [Hg(L)](ClO4)(2) and [Cu(L)](ClO4), by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of Hg(II) and ...
Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells
(Springer, 2018)
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Complete epithelial to mesenchymal transition (EMT) has long been considered as a crucial step for metastasis initiation. It ...
Synhesis and genotoxic activities of five 2-aryl-substituted-benzothiazole derivatives
(Chiminform Data S A, 2006)
Five 2-aryl-substituted-benzothiazoles were synthesized from o-amino-thiophenol and their structural assignments were made by H-1-NMR. Mutagenicily of derivatives was tested by Salmonella microsome assay using TA98 and ...
Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro
(Wiley, 2008)
Naturally occurring compounds can have protective effects towards mutagens and carcinogens as shown by numerous studies. In the present study, the genotoxic/antigenotoxic activities of the extract from lichen Cetraria ...