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Toplam kayıt 21, listelenen: 1-10
Gold(III) compounds-mediated inhibition of lung cancer cell proliferation
(Lippincott Williams & Wilkins, 2016)
Research on chemotherapeutics for lung cancer is crucial for designing a new therapeutic strategy against malignant lung tumors. Although radiotherapy and chemotherapy, which are not selective for cancer cells and exert ...
Investigation of the pharmacological profiles of dinuclear metal complexes as novel, potent and selective cytotoxic agents against leas-transformed cells
(Elsevier Science BV, 2014)
Around the world scientists try to design successful cures against still incurable diseases, especially cancers. New targets for prevention and new agents for therapy need to be identified. We synthesized novel metal ...
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
(Pergamon-Elsevier Science LTD, 2013)
Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ...
Biological activities of Cu(II) and Hg(II) complexes of a heptadentate Schiff base ligand
(Tubitak Scientific & Technical Research Council Turkey, 2010)
Two metal complexes were synthesized as [Hg(L)](ClO4)(2) and [Cu(L)](ClO4), by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of Hg(II) and ...
Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells
(SAGE Publications LTD, 2018)
Background: Acrylamide is a very common compound even reaching up to our daily foods. It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, human lung ...
Effects of Gibberellic Acid on Hemocytes of Galleria mellonella L. (Lepidoptera: Pyralidae)
(Oxford University Press Inc, 2012)
The impacts of different doses of the plant growth regulator gibberellic acid (GA(3)) in diet on the number of total and differential hemocytes, frequency of apoptotic, and necrotic hemocytes, mitotic indices, encapsulation, ...
The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line
(Springer, 2018)
Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat ...
Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7
(Springer, 2016)
Metal based drugs have successfully been used in both the detection and treatment of different disease states. The antibacterial features of metal ion silver are well documented. Most recently, metal ion silver has been ...
Melatonin induces antiproliferative activity through modulation of apoptotic pathway in H-ras oncogene transformed 5RP7 cells
(Tubitak Scientific & Technical Research Council Turkey, 2015)
In the present study, cytotoxic and apoptotic effects of melatonin were investigated on H-ras oncogene transformed rat embryo fibroblast 5RP7 cells. Melatonin inhibited cell growth and induced apoptosis in 5RP7 cells. We ...
The apoptotic and genomic studies on A549 cell line induced by silver nitrate
(SAGE Publications LTD, 2017)
Lung cancer is the leading cause of male cancer deaths worldwide. Metal-based anticancer drugs have evolved significantly during the past decades. Recently, silver ions have been investigated for their anticancer effects. ...