Browsing Makale Koleksiyonu by Title
Now showing items 46-65 of 76
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Ornidazole incorporated chitosan nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Physicochemical characterization and dissolution properties of cinnarizine solid dispersions
(2005)Sudaki çözünürlüğü düşük olarak bilinen kalsiyum antagonisti sinnarizinin biyoyararlanımı değişken veya düşüktür. Bu özellikteki bir ilaç materyalinin çözünme davranışının iyileştirilmesi, oral biyoyararlanımı geliştirebilir. ... -
A polarographic study on dipyridamole and its determination in commercial tablets
(1991)The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KC1, 20 % (v/v) ethanol and buffer solutions is described in this study. Morphologically ... -
A Polarographic Study on Dipyridamole and Its Determination in Commercial Tablets
(Marcel Dekker Inc, 1991)The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KCl, 20% (v/v) ethanol and buffer solutions is described in this study. Morphologically ... -
Polymeric Cyclosporine-A Nanoparticles for Ocular Application
(Amer Scientific Publishers, 2011)In the present study, cyclosporine A (CsA) was incorporated successfully into cationic Eudragit(R) RS 100 nanoparticles (EPNs) aiming ocular application. Physicochemical characterization of the EPNs prepared was performed ... -
Preparation and characterization of methotrexate-loaded microcapsules
(Taylor & Francis LTD, 2014)Methotrexate (MTX) has toxic effect to healthy tissues. Microencapsulation coats particles with a functional coat to optimize storage stability and to modulate release. In the present study, a new MTX encapsulated microcapsules ... -
Preparation and characterization of polymeric and lipid nanoparticles of pilocarpine HCl for ocular application
(Informa Healthcare, 2013)Pilocarpine is used topically in the treatment of glaucoma. Various studies were performed to improve the bioavailability and prolong the residence time of drugs in ocular drug delivery. Drug loaded polymeric and lipid ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
(İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Preparation and in vitro evaluation of controlled release hydrophilic matrix tablets of ketorolac tromethamine using factorial design
(Informa Healthcare, 2008)Controlled release matrix tablets of ketorolac tromethamine (KT) were prepared by direct compression technique using cellulose derivatives as hydroxypropylmethyl cellulose (HPMC), hydroxyethyl cellulose (HEC), and carboxymethyl ... -
Preparation and in vitro evaluation of in situ gelling system containing lithium carbonate for parenteral administration
(Springer Verlag, 2019)Lithium is the principal and the most effective drug in the treatment of bipolar disorder since the middle of the previous century. However, narrow therapeutic range and side effect profile of lithium necessitate its careful ... -
Preparation of prolonged release clarithromycin microparticles for oral use and their in vitro evaluation
(Pharmaceutical Soc Korea, 2006)Prolonged release microparticles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, ... -
Preparation, Characterization and In Vitro Evaluation of Dirithromycin Loaded Eudragit (R) RS 100 Nanoparticles for Topical Application
(Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The purpose of the study was to formulate dirithromycin (DR) loaded Eudragit (R) RS 100 (ERS) nanoparticles for topical application and to analyze the physical and chemical characteristics and in vitro toxicity of the ... -
Propranolol HCl imprinted polymeric microspheres: Development, characterization and dissolution
(2007)Specificity to target molecule, high selectivity and sensitivity to release and targeting were achieved using molecularly imprinted polymer (MIP) systems. In this study, propranolol HCl (PHCL) imprinted methacryloylamido ... -
Rapid analysis of verapamil in plasma by reversed phase HPLC
(1995)A modified and simple HPLC procedure has been developed for verapamil in plasma. Plasma samples have been vortex-mixed and centrifuged without any need of extraction. The analysis has been performed on a C20 reversed-phase ... -
Release of vitamin e from different topical colloidal delivery systems and their in vitro-in vivo evaluation [E Vitamininin Farkli{dotless} Topik Kolloidal Taşi{dotless}yi{dotless}ci{dotless} Sistemlerden Sali{dotless}mi{dotless} ve in vitro-in vivo Degerlendirilmesi]
(2010)In this study, topically applicable o/w microemulsion (ME), o/w simple emulsion (SE) and solid lipid nanoparticle (SLN) cosmetic delivery systems were prepared containing vitamin E. Characterization of the systems was ... -
Solid lipid nanoparticles: A possible vehicle for zinc oxide and octocrylene
(Govi-Verlag Pharmazeutischer Verlag GMBH, 2012)An efficient sunscreen formulation shows good absorption in the relevant UV range. Efficacy also means that the UV absorber must be easily incorporated in any kind of formulation. In this study, a chemical absorber, ... -
Studies on Polymeric and Lipid Nanoparticles of Ketoconazole for Ocular Administration
(Colegio Farmaceuticos Provincia De Buenos Aires, 2015)The fungistatic molecule ketoconazole was incorporated into polymeric (Eudragit (R) RS 100) and solid lipid (Gelucire (R) 44/14) nanoparticles by quasi-emulsion solvent evaporation technique aiming ocular application. ... -
Studies on prolonged release matrix tablet formulations of hydralazine hydrochloride
(2003)The purpose of this study was to prepare prolonged release tablet formulations of hydralazine hydrochloride which has been used as an antihypertensive agent. To achieve this, carbomers (Carbopol® 834, 934, 940 and 1342) ... -
Studies on rosuvastatin calcium incorporated chitosan salt nanoparticles
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2016)Cardiovascular diseases are the leading causes of death worldwide and rosuvastatin calcium (RCa) is one of the most effective drugs used for the prevention of coronary heart diseases. Considering low aqueous solubility ...