Başlık için Eczacılık Fakültesi listeleme
Toplam kayıt 1731, listelenen: 1324-1343
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A sensitive capillary LC-UV method for the simultaneous analysis of olanzapine, chlorpromazine and their FMO-mediated N-oxidation products in brain microdialysates
(Elsevier Science BV, 2017)A specific and sensitive capillary liquid chromatography-ultraviolet detection (cap-LC-UV) method in combination with a micro-extraction by packed sorbent (MEPS) sample clean-up procedure has been developed and validated ... -
Serotonerjık ve Noradrenerjık Modülasyonun Rosmarınık Asıt Analjezısıne Katkısı
(2017)Bu çalışmada, 0.3, 1 ve 3 mg/kg (p.o.) rosmarinik asitinfarelerde santral analjezik etkinliğinin sıcak-plaka vekuyruk-batırma testleri, periferal analjezik etkinliğininise asetik asit ile indüklenen kıvranma-testi ile ... -
Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms
(Wolters Kluwer Medknow Publications, 2017)This study was conducted to clarify the toxic effects of sertraline (SRT) on the reproductive system of male rats and to elucidate the underlying mechanisms. Rats were treated orally with SRT at doses of 5, 10, and 20 mg ... -
Serum Thrombopoietin Levels and Its Relationship With Thrombocytopenia in Patients With Cirrhosis
(Kowsar Publ, 2014)Background: Patients with cirrhosis usually have thrombocytopenia in discrete levels. The mechanism of thrombocytopenia is thought as splenic sequestration and destruction of platelets, impaired bone marrow generation and ... -
Sesquiterpene hydrocarbons of the essential oil of Actinolema macrolema Boiss
(Scientific Technical Research Council Turkey-Tubitak, 2013)The essential oils of Actinolema macrolema Boiss. (Apiaceae) were obtained by hydrodistillation in the first 3 (sample A) and the following 3 h (sample B) from crushed fruits and dried leaves (sample C), which were ... -
A simple and sensitive LC-ESI-MS (ion trap) method for the determination of bupropion and its major metabolite, hydroxybupropion in rat plasma and brain microdialysates
(Elsevier Science BV, 2011)A specific and highly sensitive liquid chromatography-electrospray mass spectrometry (LC-ESI-MS) method for the direct determination of bupropion (BUP) and its main metabolite hydroxybupropion (HBUP) in rat plasma and brain ... -
A Simple and Specific Hplc Method for the Determination of Atomoxetine in Pharmaceuticals and Human Plasma
(Taylor & Francis Inc, 2010)A liquid chromatographic method has been described for the determination of atomoxetine in pharmaceuticals and human plasma. Plasma samples were analyzed after a simple, one step protein precipitation with methanol, and ... -
Simple method of paroxetine determination using a single channel FIA with no in-line reaction process
(Japan Soc Analytical Chemistry, 2003)A flow-injection analysis (FIA) of paroxetine hydrochloride (PRX), a selective serotonin reuptake inhibitor (SSRI) currently used as an antidepressant drug, is described. A 0.1 mol dm(-3) acetate buffer at pH 3.07 was found ... -
A simple method to obtain essential oils from Salvia triloba L. and Laurus nobilis L. by using microwave-assisted hydrodistillation
(Verlag Z Naturforsch, 2005)A microwave-assisted hydrodistillation protocol was modified to extract essential oils from leaves of Salvia triloba L. and Laurus nobilis L. The essential oils of these plants are generally obtained by hydrodistillation ... -
The simultaneous delivery of paclitaxel and Herceptin (R) using solid lipid nanoparticles: In vitro evaluation
(Elsevier Science BV, 2016)This study was aimed at formulating Paclitaxel (R)-loaded solid lipid nanoparticles (SLN) complexed with Herceptin (R). The physicochemical characterizations of the SLNs/Herceptin (R) complexes such as particle size and ... -
Simultaneous Determination of Substance P and CGRP in Rat Brainstem Tissue Using LC-ESI-MS/MS Method
(Bentham Science Publ LTD, 2018)Background: Substance P and CGRP are neuropeptides that belong to the thachykinin and calcitonin family, respectively. They play an important role in neuropathic pain development and regulation. Methods: In this study, ... -
Sitophilus granarius L. (Coleoptera) Toxicity and Biological Activities of the Essential Oils of Tanacetum macrophyllum (Waldst. & Kit.) Schultz Bip.
(Japan Oil Chemists Soc, 2015)Insecticides of the natural origin are an important alternative to the synthetic insecticides that are being employed for the preserving stored products. The volatiles obtained from T. cinerariifolium (=Pyrethrum ... -
Solid lipid and chitosan particulate systems for delivery of siRNA
(Govi-Verlag Pharmazeutischer Verlag GMBH, 2015)Due to the recent advances in molecular biology, there are promising gene therapy studies for prevention and treatment of cancer, genetic and infectious diseases. Many technologies in molecular biology and biotechnology ... -
Solid lipid nanoparticles: A possible vehicle for zinc oxide and octocrylene
(Govi-Verlag Pharmazeutischer Verlag GMBH, 2012)An efficient sunscreen formulation shows good absorption in the relevant UV range. Efficacy also means that the UV absorber must be easily incorporated in any kind of formulation. In this study, a chemical absorber, ... -
Solid lipid non-particles (SLN) [Kati lipit nanopartiküller (SLN)]
(2000)Colloidal drug delivery systems are one of the subjects investigated intensively in the pharmaceutical field, in recent years. Those systems include microspheres, polymeric nanoparticles, liposomes and fat emulsions. An ... -
Some 1-substituted 3-aryl-1,4-dihydro-1,2,4-triazino[4,3-a]- benzimidazoles and their vasodilatory activities
(Societa Chimica Italiana, 1997)In this study, some 1-substituted 3-aryl-1,4-dihydro-1,2,4- triazino[4,3-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their vasodilatory activities were examined. It was found that ... -
Some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives and their antimicrobial activities
(2005)In this study, some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives have been synthesized by reacting 3-alkyl-7-oxothiazolo[4,5-d]pyrimidin-2(3H)-thiones with various ?-bromoacetophenones. ... -
Some 6-substituted 3-aryl-7-oxothiazolo[4,5-d]pyrimidin-2(3H)-thione derivatives and their antimicrobial activities
(Taylor & Francis LTD, 2007)In this study, 3-aryl-6-substituted thiazolopyrimidin-2(3H)-thione derivatives 4 and 6 have been synthesized by reacting thiazolopyrimidines 2 with omega-bromoacetophenone 3 and 2-chloro-N-(2-thiazolyl)acetamides 5. The ... -
Some new 2,3-dihydro-3 benzofuranamine derivatives
(1998)In this study, four series of the compounds (i.e. 2, 3, 4 and 5) were synthesized using the 2-chloro-N-(2,3-dihydro-3-benzofuryl)acetamides. The structures of the compounds were elucidated by IR, 1H-NMR, MASS spectroscopy ... -
Some new 4-aryl-2-thiazolylhydrazones
(1997)In this study, three series of 4-aryl-2-thiazolylhydrazones were synthesized using three different thiosemicarbazones. Structures of the compounds were elucidated by IR, 1H NMR and elemental analysis. The prepared compounds ...