Browsing European Journal of Life Sciences by Publisher "Anadolu Üniversitesi"
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Antimicrobial and antioxidant activities of Sideritis lanata L. extracts
(Anadolu Üniversitesi, 2022)Sideritis L. (Lamiaceae) is represented by 45 species in Flora of Turkey. Sideritis lanata L. (Hairy ironwort) is located in the north-west, west, south-west and central Anatolia. Mountain tea (Sideritis plants) is used ... -
Arum italicum Miller tuber extracts: Evaluation of synergistic activities with ciprofloxacin against some pathogens
(Anadolu Üniversitesi, 2022)Antibiotic misuse or overuse leads antibiotic resistance. Antibiotic resistant bacteria infections cause significant clinical problem. Recently, antibiotic resistant bacteria numbers have increased, this situation has ... -
Capsaicin inhibits proliferation and induces apoptosis in human lung adenocarcinoma A549 cell line
(Anadolu Üniversitesi, 2022)Capsaicin is the main component of many hot peppers, exerts anticancer effects on various cancer cells by inducing apoptotic pathways. In addition, the ineffectiveness of this apoptotic effect of capsaicin on healthy cells ... -
Chaerophyllum libanoticum Boiss. Et Kotschy: The fruit essential oil, composition, skin-whitening and antioxidant activities
(Anadolu Üniversitesi, 2022)This study was aimed to evaluate the essential oil composition of Chaerophyllum libanoticum fruits and its potential uses in the cosmetic industry. The essential oil was analyzed by Gas Chromatography (GC) and Gas ... -
Comparison of apoptotic effects of lupeol on A549 and C6 cell lines
(Anadolu Üniversitesi, 2024)Lupeol compound is a cyclic triterpene alcohol that is widely found in plants. The compound lupeol has been reported to exhibit antitumor, anti-inflammatory, anxiolytic, neuroprotective and hepatoprotective effects. Recent ... -
COX inhibitory profiles of a series of thiadiazole-benzothiazole hybrids
(Anadolu Üniversitesi, 2024)In an endeavour to identify small molecule COX-1 inhibitors, a colorimetric assay protocol was applied for the in vitro evaluation of COX-1 and 2 inhibitory potential of a series of thiadiazole-benzothiazole hybrids. The ... -
Design, synthesis and in vitro COX inhibitory profiles of a new series of tetrazole-based hydrazones
(Anadolu Üniversitesi, 2022)Inhibition of cyclooxygenases (COXs), by selective and nonselective inhibitors, is a favorable approach for pharmacologic intervention in a variety of disorders such as cancer. For this purpose, a new class of tetrazole-hydrazone ... -
Determination of cytotoxic, antioxidant activities and LC/MS-MS profiles of three endemic Verbascum L. species
(Anadolu Üniversitesi, 2023)The Verbascum genus includes many species used in folk medicine or the treatment of various diseases. In this study, the cytotoxic, antioxidant activity, and LC/MS-MS profiles of three Verbascum species, which are endemic ... -
Determination of potential probiotic properties of lactic acid bacteria isolated from colostrum milk
(Anadolu Üniversitesi, 2023)Colostrum milk has been used as a source for isolating many probiotic bacteria since it contains many helpful probiotic microorganisms. Because of the huge microorganism diversity and functionality of colostrum, there is ... -
Essential oil composition and antimicrobial activity of Glaucosciadium cordifolium (Boiss.) Burtt. & Davis
(Anadolu Üniversitesi, 2022)Glaucosciadium cordifolium (Boiss.) Burtt. & Davis, which is a monotypic species naturally grown in Turkey belonging to the Apiaceae (Umbelliferae) family. In this study, the essential oil obtained from G. cordifolium was ... -
Etiopathogenesis of depression and experimental depression models used in preclinical studies
(Anadolu Üniversitesi, 2023)Depression is the most frequent psychiatric illness among mood disorders, affecting approximately 10% of adults. Especially recurrent and moderate/severe depression can become a serious public health problem by impairing ... -
Evaluating attitudes of pharmacy students toward pharmaceutical side effect pictograms: Ankara sample
(Anadolu Üniversitesi, 2024)Pictograms are graphic symbols that facilitate international communications and express objects and the meaning of these objects. Using pictograms in health is essential to informing patients, especially in cases such as ... -
Evaluation of in vitro hepatotoxicity of perampanel in comparison with carbamazepine: old versus new
(Anadolu Üniversitesi, 2023)Since the liver metabolizes many drugs, including antiepileptics, this organ is the main target of drug-induced damage. There is very little data on hepatotoxicity due to carbamazepine and perampanel metabolized in the ... -
Evaluation of volatile components of Achillea millefolium L. essential oil
(Anadolu Üniversitesi, 2023)The genus Achillea (Asteraceae) is distributed in Europe and the Middle East and has approximately 140 endemic species. There are 40 Achillea sp. in the Turkish flora and 20 of them are endemic. This genus has a widespread ... -
Focusing on the moderately active compound (MAC) in the design and development of strategies to optimize the apoptotic effect by molecular mechanics techniques
(Anadolu Üniversitesi, 2022)Today, chemotherapeutic agents are mostly used to fight cancer in clinics. But even though they have selectivity for cancer cells, their mechanism of action could result in necrosis. Therefore, we aimed to suggest new ... -
Geographical impact on essential oil composition of endemic Salvia absconditiflora collected from different parts of Turkey
(Anadolu Üniversitesi, 2022)This study was carried out to determine the content of the essential oils of Salvia absconditiflora Greuter & Burdet populations which are naturally found in Mediterranean, Iran-Turan and Euro-Sibirya phytogeographical ... -
High-density lipoprotein: Quality is more important than quantity!
(Anadolu Üniversitesi, 2022)High density lipoproteins (HDLs) are complex lipid carriers which replace their own structures and functions according to different conditions including healthy or pathological status. HDL has substantial roles in reverse ... -
HPLC method for simultaneous quantification of lumacaftor and ivacaftor bulk and pharmaceutical formulations
(Anadolu Üniversitesi, 2023)In 2015, the Food and Drug Administration granted approval for the use of lumacaftor 200 mg and ivacaftor 125 mg in the treatment of cystic fibrosis patients who possess the F508del mutation, namely those who are 12 years ... -
Knowledge and behavior of community pharmacists towards detecting drug-drug interactions
(Anadolu Üniversitesi, 2023)Drug-drug interactions (DDIs) are preventable medication errors that can cause severe adverse effects for patients, which often involve more than one mechanism. Healthcare practitioners, especially community pharmacists, ... -
Latest research about active pharmaceutical ingredient loaded Poly Lactic Acid-co-Glycolic Acid (PLGA) based drug delivery system in Türkiye
(Anadolu Üniversitesi, 2022)Some of the most well-engineered and produced biomaterials are polyesters based on polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers, polylactic acid co-glycolic acid (PLGA). In controlled release systems, ...