Yazar "Demirayak, Şeref" için listeleme
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Some thiazolylaminopyrrole derivatives and their antimicrobial activity
In this study, some ethyl 1-(4-arylthiazol-2-yl)amino-2-methyl-5-aryl-1H-pyrrole-3-carboxylic acid derivatives were obtained by reacting 1-(2-methyl-3-carbethoxy-5-arylpyrrol-1-yl)thioureas with ?-bromoacetophenone ... -
Spectroscopic Determination and Evaluation of Acidity Constants for Some Drug Precursor 2-Amino-4-(3-or 4-substituted phenyl) Thiazole Derivatives
Öğretir, Cemil; Demirayak, Şeref; Duran, Murat (American Chemical Society, 2010)Acid dissociation constants, K(a), of eight drug precursor 2-amino-4-(3- or 4-substituted phenyl) thiazole derivatives were determined using a UV-vis spectroscopic technique. The obtained K(a) values were evaluated by ... -
Spectroscopic determination of acid dissociation constants of some biologically active 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives
Öğretir, Cemil; Yarlıgan, S; Demirayak, Şeref (American Chemical Society, 2002)The acid dissociation constants, pK(a), of twelve biologically active 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives were determined using spectroscopic techniques. Elucidation of the structure-reactivity relationships ... -
Spectroscopic determination of acid dissociation constants of some pyridyl-substituted 2-aminothiazole derivatives
Öğretir, Cemil; Demirayak, Şeref; Tay, Naime Funda (American Chemical Society, 2006)The acid dissociation constants, K-a, of nine biologically active 2-amino-4-(x-pyridyl)- thiazole, 2-methylimino-3-methyl- 4-(x-pyridyl)- 2,3-dihydrothiazole, and 2-methylamino-4-(x-pyridyl)- 2,3-dihydrothiazole were ... -
Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives
Şahin, Zafer; Ertaş, Merve; Berk, Barkın; Biltekin, Sevde Nur; Yurttaş, Leyla; Demirayak, Şeref (Pergamon-Elsevier Science LTD, 2018)Steroidal and non-steroidal aromatase inhibitors target the suppression of estrogen biosynthesis in the treatment of breast cancer. Researchers have increasingly focused on developing non-steroidal derivatives for their ... -
Studies on the ionisation constants and copper complex of 2-aminomethylbenzimidazole and its 5-nitro derivative
Demirayak, Şeref; Tuncel, M.; Ergün, Bülent (1991)[No abstract available] -
Studies on the synthesis of some new antipyrine derivatives
Some new 4-(4, 5-diarylimidazole-2-yl) antipyrine, 4-(5-substituted benzimidazole-2-yl) antipyrine and 4-(phenantroimidazole-2-yl) antipyrine derivatives were synthesised. The structure elucidations of the compounds were ... -
Synthesis and analgesic activities of some 2-(benzazolylacetyl)amino-3-ethoxycarbonylthiophene derivatives
Demirayak, Şeref; Karaburun, AC; Kayagil, İsmail; Uçucu, Ümit; Arslan, Rana (Taylor & Francis LTD, 2005)In this study, some 2-[2-(benzazole-2-thioxy)acetylamino]-3-ethoxycai-bonylthiophene and 2-[2-(benzazole-1-yl)acetylamino]-3-ethoxycarbonylthiophene compounds were obtained by the reaction of 2-chloroacetylamino-3-ethoxy ... -
Synthesis and anti-cancer activity evaluation of new aurone derivatives
Demirayak, Şeref; Yurttaş, Leyla; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Kayagil, İsmail (Taylor & Francis LTD, 2015)In this study, we have synthesized 2-[3-or 4-(2-aryl-2-oxoethoxy) arylidene] benzofuran-3-one derivatives (D1-D38) and evaluated their anti-cancer activities. The final compounds were obtained in multistep synthesis reactions ... -
Synthesis and antibacterial activities of some 1-[2-(substituted pyrrol- 1-yl)ethyl]-2-methyl-5-nitroimidazole derivatives
Demirayak, Şeref; Karaburun, Ahmet Çağrı; Kiraz, N. (Elsevier Masson SAS, 1999)In this study, some 1-[2-(substituted pyrrol-1-yl)ethyl]-2-methyl-5- nitroimidazole derivatives were synthesized by reacting 2-(2-methyl-5-nitro- 1H-imidazolyl)ethylamine dihydrochloride, which was prepared using metronidazole, ... -
Synthesis and antibacterial and antifungal evolution of some ethyl 1- aryloxyacetylamino-5-arylpyrrole-3-carboxylic acid derivatives
In this study some ethyl 1-aryloxyacetylamino-2methyl-5-aryl-1H-pyrrole- 3-carboxylic acid derivatives were obtained by reacting some aryloxyacetylhydrazide and 1-aryl-3-carbethoxy-1,4-pentadione derivatives. The antibacterial ... -
Synthesis and Anticancer Activities of Some Thiazole Derivatives
Kayagil, İsmail; Demirayak, Şeref (Taylor & Francis LTD, 2009)In this study, 2-substituted 4-[3/4-(4-arylthiazole-2-yl) aminophenyl] thiazole derivatives and 2-[4-[2-substituted 4-methylthiazole-5-yl]thiazole-2-yl] amino-5-arylidenethiazoline-4-one derivatives have been synthesized. ... -
Synthesis and anticancer activity of some 1,2,3-trisubstituted pyrazinobenzimidazole derivatives
Demirayak, Şeref; Yurttaş, Leyla (Taylor & Francis LTD, 2014)The synthesis of some new pyrazino[1,2-a]benzimidazole derivatives and investigation of their anticancer activities were aimed in this work. Thus, 2-acetylbenzimidazole was reacted with appropriate alpha-bromoacetophenones ... -
Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives
Karaburun, Ahmet Çağrı; Gündoğdu-Karaburun, Nalan; Yurttaş, Leyla; Kayagil, İsmail; Demirayak, Şeref (Bentham Science Publ LTD, 2019)Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied. Methods: ... -
Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Demirayak, Şeref; Kayagil, İsmail; Yurttaş, Leyla (Bentham Science Publ LTD, 2014)The synthesis of 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1one derivatives and the investigation of their anticancer activity were studied. 2-(3- or 4-Hydroxybenzylidene) ... -
Synthesis and anticancer and anti-HIV testing of some pyrazino[1,2-a]benzimidazole derivatives
In this study, some 1-methylene-2,3-diaryl-1,2-dihydropyrazino[1,2-a]benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives were synthesised. The structure elucidation of the compounds was ... -
Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
Benkli, Kadriye; Gündoğdu-Karaburun, N; Karaburun, Ahmet Çağrı; Uçucu, Ümit; Demirayak, Şeref; Kiraz, N (Pharmaceutical Society Korea, 2003)In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. ... -
Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes
Gündoğdu-Karaburun, Nalan; Benkli, Kadriye; Tunalı, Yağmur; Uçucu, Ümit; Demirayak, Şeref (Elsevier France-Editions Scientifiques Medicales Elsevier, 2006)In this study, some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketones, aryl (3-methyl-benzofuran-2-yl) ketoximes and aryl [3(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes were synthesised ... -
Synthesis and Antifungal Activities of Some Aryl Naphthofuran Ketoximes
Karaburun, Ahmet Çağrı; Gündoğdu-Karaburun, Nalan; Uçucu, Ümit; Demirayak, Şeref (Bentham Science Publ LTD, 2011)In this study, some aryl naphtho[2,1-b] furan-2-yl ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR and MASS spectroscopic data and elemental ... -
Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes
Demirayak, Şeref; Uçucu, Ümit; Benkli, Kadriye; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Akar, D; Kiraz, N (Elsevier Science Sa, 2002)In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses ...