Yazar "Özaslan, Muhammet Serhat" için listeleme
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Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes
Demir, Yeliz; Taslimi, Parham; Özaslan, Muhammet Serhat; Öztaşkın, Necla; Çetinkaya, Yasin; Gülçin, İlhami; Göksu, Süleyman (Wiley-V C H Verlag GMBH, 2018)Aldose reductase converts glucose to sorbitol in the polyol pathway. It is an important enzyme to prevent diabetic complications. In this study, we studied the inhibitory effects of bromophenol derivatives on aldose reductase ... -
The behavior of some chalcones on acetylcholinesterase and carbonic anhydrase activity
Aslan, Hatice Esra; Demir, Y.; Özaslan, Muhammet Serhat; Türkan, F.; Beydemir, Ş.; Küfrevioğlu, Ö. I. (Taylor and Francis Ltd, 2019)Carbonic anhydrase (CA) has a key role in respiration, carbon dioxide and bicarbonate transport. Acetylcholinesterase (AChE) is a serine hydrolase and mostly abundant at neuromuscular junctions and cholinergic brain synapses. ... -
Evaluation of chalcones as inhibitors of glutathione S-transferase
Özaslan, Muhammet Serhat; Demir, Yeliz; Aslan, Hatice Esra; Beydemir, Şükrü; Kufrevioğlu, Ömer İrfan (Wiley, 2018)Glutathione S-transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were ... -
Inhibition effects of quinones on aldose reductase: Antidiabetic properties
Demir, Yeliz; Özaslan, Muhammet Serhat; Duran, Hatice Esra; Kufrevioğlu, Ömer İrfan; Beydemir, Şükrü (Elsevier, 2019)Diabetes mellitus is a chronic metabolic disease characterized by abnormal glucose metabolism. Aldose reductase (AR) is the first enzyme in the polyol pathway and converts glucose to sorbitol. It plays a vital role as a ...
