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Design, synthesis, monoamine oxidase inhibition and docking studies of new dithiocarbamate derivatives bearing benzylamine moiety
Kaya Çavuşoğlu, Betül; Sağlık, Begüm Nurpelin; Özkay, Yusuf; İnci, Beril; Kaplancıklı, Zafer Asım (Academic Press Inc Elsevier Science, 2018)A new series of thirteen 2-[(4-fluorophenyl)(4-nitrobenzyl) amino]-2-oxoethyl-1-substituted-carbodithio ate derivatives (4a-4m) were synthesized and tested for their human monoamine oxidase A and B (hMAO-A and hMAO-B) ... -
Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity
Can, Nafiz Öncü; Osmaniye, Derya; Levent, Serkan; Sağlık, Begüm Nurpelin; İnci, Beril; Ilgın, Sinem; Kaplancıklı, Zafer Asım (MDPI, 2017)In the present work, 14 new 1-substituted-2-phenylhydrazone derivatives were synthesized to evaluate their inhibitory activity against hMAO enzymes. The structures of the newly synthesized hydrazones 2a-2n were characterized ...