Yazar "Şahin, Z." için listeleme
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Antimicrobial evaluation of trisubstituted 2-piperazinyl thiazoles
Giray, B.; Yurttaş, Leyla; Şahin, Z.; Berk, B.; Demirayak, Şeref (İstanbul Medipol University, 2019)Thiazole and basic nitrogen containing rings are important chemical moieties of antimicrobial drugs. In recent, third generation cephalosporins include thiazole ring system. In this study, we synthesized 33 piperazine ... -
Synthesis and antimicrobial activity evaluation of novel nitrofuranthiazoles
Yurttaş, Leyla; Şahin, Z.; Er, S.; Demirayak, Şeref (University of Istanbul, 2016)In this work, six novel 4-aryl-2-[2-((5-nitrofuran-2-yl)methylene)hydrazinyl] thiazole derivatives (2a-f) were synthesized starting from 5-nitro-2-furaldehyde diacetate by using Hantzsch thiazole synthesis. The antimicrobial ... -
Synthesis of novel 3, 5, 6-trisubstituted triazine derivatives and their biological activity evaluation as potential antitumor and anti-inflammatory agents
Yurttaş, Leyla; Şahin, Z.; Çiftçi, Gülsen Akalın; Temel, Halide Edip; Demirayak, Şeref (University of Istanbul, 2016)In this study, new 3, 5, 6-trisubstituted 1, 2, 4-triazine derivatives (1-9) were synthesized and their structures were determined by using NMR, IR and Mass spectroscopic methods. In vitro antitumor activities against MCF-7 ...