Yazar "Abu Mohsen, Usama" için listeleme
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Bazı 1-metilen-2,3-diaril-1,2-dihidropirazino-[1,2-a]benzimidazol türevlerinin sentezi ve antikanser ve anti-hiv etkilerinin araştırılması
Abu Mohsen, Usama (Anadolu Üniversitesi, 1999)Bu çalışmada, bazı 1-metilen-2,3-diaril-1,2-dihidropirazino[1,2-a] bezimidazol türevlerinin sentezlenmesi ve antikanser ve anti-HIV-1 etkilerinin araştırılması amaçlandı. Bileşikleri sentez için önce, 2-asetilbenzimidazol ... -
Bazı pirazino [1,2-a] benzimidazol türevlerinin sentezi ve antimikrobiyal etkilerinin araştırılması
Abu Mohsen, Usama (Anadolu Üniversitesi, 1996)Bu çalışmada, bazı 1-(benzimidazol-2-il)-3-aril-2-propenon ve a-bromoasetofenon türevlerinden hareketle hazırlanan I-[1-(2-fenil-2 okzoetil)benzimidazol-2-il]-3-aril-2-propenon türevleri amonyum asetat ile asetik asit ... -
A facile synthesis of 2-aryl-4,5-di(2-thienyl)imidazoles under microwave irradiation and their antimicrobial activities
In this study, some 2-aryl-4,5-dithienylimidazoles were synthesized by reacting di-(2-thienyl)ethandione and a suitable aromatic aldehyde in the presence of ammonium acetate in acetic acid. Either the classical reflux ... -
Studies on hydrazide-hydrazones derivatives as acetylcholinesterase inhibitors
Abu Mohsen, Usama; Koçyiğit-Kaymakçıoğlu, Bedia; Oruç-Emre, Emine Elçin; Kaplancıklı, Zafer Asım; Rollas, Sevim (Aves Press LTD, 2015)Objective: Fifteen hidrazide-hydrazone derivatives were synthesized and evaluated for their ability to inhibit acetylcholinesterase (AChE) using a modification of Ellman's spectrophotometric method. Methods: Anti-acetylc ... -
Synthesis and anticancer and anti-HIV testing of some pyrazino[1,2-a]benzimidazole derivatives
In this study, some 1-methylene-2,3-diaryl-1,2-dihydropyrazino[1,2-a]benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives were synthesised. The structure elucidation of the compounds was ... -
Synthesis and antifungal activity of new hydrazide derivatives
Turan, Gülhan; Altıntop, Mehlika Dilek; Özdemir, Ahmet; Demirci, Fatih; Abu Mohsen, Usama; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2013)In this study, nine new hydrazide derivatives were synthesized. The reaction of 2-[(5,6,7,8-tetrahydronaphthalen-2-yl) oxy]acetohydrazide with various benzaldehydes or acetophenones resulted in N'-substituted-2-[(5,6,7,8 ... -
Synthesis and antimicrobial activity of benzimidazole-based acetamide derivatives
Altıntop, Mehlika Dilek; Abu Mohsen, Usama; Özkay, Yusuf; Demirel, Rasime; Kaplancıklı, Zafer Asım (Turkish Pharmacists Association, 2015)In the current work, new benzimidazole-based acetamide derivatives (2a-u) were synthesized and screened for their in vitro antimicrobial activity. Among these derivatives, compounds 2b-2g were found to be the most promising ... -
Synthesis and Antimicrobial Activity of New Pyrimidine-Hydrazones
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Turan, Gülhan; Özdemir, Ahmet; Göğer, Gamze; Demirci, Fatih; Abu Mohsen, Usama (Bentham Science Publ LTD, 2014)The synthesis of twelve new pyrimidine hydrazone derivatives and subsequent evaluation of their antimicrobial activities were the aims of this present work. The intermediate product 2-[(pyrimidin-2-yl)thio]acetohydrazide ... -
Synthesis and antiproliferative activity of new 1,5-disubstituted tetrazoles bearing hydrazone moiety
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Özdemir, Ahmet; Turan, Gülhan; Çiftçi, Gülsen Akalın; Yıldırım, Şafak Ulusoylar; Abu Mohsen, Usama (Springer Birkhauser, 2014)A new class of tetrazole-hydrazone derivatives including chloro-substituted phenyl moiety were synthesized to perform anticancer activity screening. The structural elucidation of the compounds was performed by IR, H-1 NMR, ... -
Synthesis and biological evaluation of some dibenzofuran-piperazine derivatives
Yurttaş, Leyla; Abu Mohsen, Usama; Özkan, Yeşim; Çobanoğlu, Simla; Levent, Serkan; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2016)In the present paper, a novel series of dibenzofuran-piperazine derivatives were synthesized via the treatment of N-(2-methoxy-3-dibenzofuranyl)-2-chloroacetamide with substituted piperazine derivatives. The chemical ... -
Synthesis and Biological Evaluation of Some New Amide Moiety Bearing Quinoxaline Derivatives as Antimicrobial Agents
Abu Mohsen, Usama; Yurttaş, Leyla; Acar, U.; Özkay, Yusuf; Kaplancıklı, Zafer Asım; Karaca Gencer, Hülya; Cantürk, Zerrin (Georg Thieme Verlag Kg, 2015)In this study, we aimed to synthesize some new quinoxaline derivatives bearing amide moiety and to evaluate their antimicrobial activity. A set of 16 novel compounds of N-[2,3-bis(4-methoxy/methylphenyl)quinoxalin-6-yl]- ... -
Synthesis and biological screening of some novel triazole derivatives
Acar, U.; Abu Mohsen, Usama; Özkay, Yusuf; Karaca, H.; Kaplancıklı, Zafer Asım (Turkish Pharmacists Association, 2015)In the present study 15 novel triazole compounds were synthesized in order to investigate their anticandidal and anticholinesterase activities. Structures of the synthesized compounds were elucidated by spectral data and ... -
The synthesis and evaluation of anti-acetylcholinesterase activity of some 4(3H)-quinazolinone derivatives bearing substituted 1,3,4- thiadiazole
Uraz, Mine; Karakus, Sevgi; Abu Mohsen, Usama; Kaplancıklı, Zafer Asım; Rollas, Sevim (Marmara University, Fac Medicine, 2017)In the present study, a series of 4(3H)-quinazolinone derivatives (5a-f) were synthesized through the cylization reaction of substituted 1,3,4-thiadiazoles containing an aromatic primary amin and anthranilic acid in the ... -
Synthesis and Evaluation of Bis-pyrazoline Derivatives as Potential Antimicrobial Agents
Altıntop, Mehlika Dilek; Abu Mohsen, Usama; Karaca, Hülya; Cantürk, Zerrin; Özdemir, Ahmet (Bentham Science Publ LTD, 2014)In the present study, 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazole-1-(4-arylthiazol-2-yl)] derivatives (3a-h) were obtained via the reaction of 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazo ... -
Synthesis and In vitro Evaluation of Thiadiazole Derivatives as AChE, BuChE and LOX Inhibitors
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Abu Mohsen, Usama; Temel, Halide Edip; Çiftçi, Gülsen Akalın; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2014)N'-Benzylidene-2-[[5-(phenylamino)-1,3,4-thiadiazol-2-yl]thio]acetohydrazide derivatives (5a-p) were synthesized to screen for their AChE, BuChE and LOX inhibitory activity. The CCK-8 assay was also carried out to determine ... -
Synthesis of some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives and their antimicrobial activities
Some 1-(2-arylvinyl)-3-arylhyrazino[1,2-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their antibacterial and antifungal activities were examined. None of the compounds proved to be ... -
Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Özdemir, Ahmet; Turan, Gülhan; İşcan, Gökalp; Akalın Çiftçi, Gülsen; Abu Mohsen, Usama (Taylor & Francis LTD, 2014)In this study, 14 different 2-[(1-methyl-1H-tetrazole-5-yl)thio]-1-(phenyl) ethanone derivatives (1-14) were synthesized. The structures of the obtained compounds were elucidated using IR, H-1-NMR, C-13-NMR and FAB(+)-MS ... -
Synthesis, anticandidal activity, and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains
Yurttaş, Leyla; Özkay, Yusuf; Demirci, Fatih; Göğer, Gamze; Yıldırım, Şafak Ulusoylar; Abu Mohsen, Usama; Kaplancıklı, Zafer Asım (Scientific Technical Research Council Turkey-Tubitak, 2014)Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal activity and cytotoxicity. The structures of the obtained final compounds (6a-j) were confirmed by ...
