Yazar "Alim, Zuhal" için listeleme
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Assessment of the inhibitory effects and molecular docking of some sulfonamides on human serum paraoxonase 1
Alim, Zuhal; Kılıç, Deryanur; Köksal, Zeynep; Beydemir, Şükrü; Özdemir, Hasan (Wiley, 2017)Paraoxonase-1 (PON1) is an organophosphate hydrolyzer and antiatherogenic enzyme. Due to the PON1's crucial functions, inhibitors and activators of PON1 must be known for pharmacological applications. In this study, we ... -
Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study
Alim, Zuhal; Kılınç, Namık; Şengül, Bülent; Beydemir, Şükrü (Taylor & Francis LTD, 2017)Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 ... -
Mechanism of capsaicin inhibition of aldose reductase activity
Alim, Zuhal; Kılınç, Namık; Şengül, Bülent; Beydemir, Şükrü (Wiley, 2017)Aldose reductase (AR) inhibitors play a vital importance as a potential therapeutic and preventive medicine when it comes to hyperglycemia associated diabetic complications. Additionally, capsaicin is used as a food additive ...