Yazar "Altan, Vecdi Melih" için listeleme
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Altered Alpha-Adrenergic Responses of Vas-Deferens to Noradrenaline and Tyramine From Rats With Short-Term and Long-Term Alloxan Diabetes
Öztürk, Yusuf; Yıldızoğulları, N; Altan, Vecdi Melih (Pergamon-Elsevier Science LTD, 1994)1. Functional and morphological abnormalities in vas deferens have been reported by both experimental and clinical studies as a cause of genital function abnormalities in diabetic males. 2. In the present study, contractile ... -
Altered responses to calcium and trifluoperazine in K+-depolarized duodenum from alloxan diabetic rats
Contractile responses to calcium were examined in the K+-depolarized duodenum from normal and alloxan-diabetic rats. In addition, verapamil and trifluoperazine which are well-known calcium channel blocker and calmodulin ... -
Basal and histamine-induced gastric acid secretion in alloxan diabetic rats
Özçelikay, A. T.; Altan, Vecdi Melih; Yıldızoğlu-Arı, N.; AltınKurt, Onur; Onur, F.; Öztürk, Yusuf (1993)1. 1. Effects of alloxan-induced diabetes on the rat gastric acid secretion were investigated using a number of biostatistical models described earlier. 2. 2. Histamine-induced gastric acid secretion was found to be decreased ... -
Beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in streptozotocin-diabetic rats: A contributing role of protein biosynthesis
The beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in experimentally diabetic rats has been reported. The effects of streptozotocin-induced diabetes and insulin on the isolated rat ... -
Beta-Adrenergic Responsiveness of the Gastrointestinal-Tract in Diabetic Rats
Öztürk, Yusuf; Altan, Vecdi Melih; Yıldızoğulları, N (Munksgaard Int Publ LTD, 1992)Recently, decreased gastrointestinal beta-adrenergic responses in experimental diabetes have been demonstrated. Gastrointestinal responses to beta-adrenoceptor agonists are impaired in both insulin-dependent and ... -
Bradykinin Receptors in Intestinal Smooth Muscles and Their Postreceptor Events Related to Calcium
Öztürk, Yusuf; Altan, Vecdi Melih; Yıldızoğulları, N; Altınkurt, O (Hindawi LTD, 1993)THE effects of trifluoperazine and verapamil on bradykinin- and des-Arg9-bradykinin induced responses of isolated rat duodenum and guinea-pig ileum were investigated to elucidate post-bradykinin receptor events. Verapamil ... -
Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: Effects of insulin therapy and calmodulin antagonism
Öztürk, Yusuf; Aydın, Süleyman; Özçelikay, A. T.; Altan, Vecdi Melih; YıldızoğluArı, N (Elsevier Science BV, 1997)The effects of experimental diabetes and insulin treatment on the decreased reactivity of isolated rat duodenum to KCI and calmidazolium, a specific calmodulin antagonist, were examined. After 8 weeks of streptozotocin ... -
Decreased Beta-Adrenergic Responses of Rat Small-Intestine Due to Non-Insulin-Dependent Diabetes
Öztürk, Yusuf; Yıldızoğulları, N; Özüarı, A; Özçelikay, At; Altan, Vecdi Melih (Elsevier Sci Ireland LTD, 1990)… -
Decreased gastro-intestinal responses to salbutamol and serotonin in streptozotocin-induced diabetes: Improving effect of insulin in vivo and in vitro
Yıldızoğlu-Arı, N.; Altınkurt, Onur; Öztürk, Yusuf; Altan, Vecdi Melih; Pekiner, C.; Karasu, Ç. (1988)1. 1. Decreased gastro-intestinal responses to salbutamol (sal) and serotonin (5-HT) in experimental diabetes have been postulated. The present study was designed to investigate whether in vivo and in vitro insulin treatments ... -
Diabetic complications in experimental models
Öztürk, Yusuf; Altan, Vecdi Melih; Arı, N. (1998)In this review, the aim is to focus on diabetic complications in experimental models of diabetis. For this purpose, complications, chiefly seen in log-term periods in various systems of animals, such as cardio vascular and ... -
Duration-dependent changes in calcium responsiveness in the alloxan-diabetic rat intestine
Öztürk, Yusuf; Altan, Vecdi Melih; Yıldızoğlu-Arı, N. (Elsevier Science Inc, 1996)Disturbances of the gastrointestinal tract that are common in diabetes mellitus seem to be related to intestinal motility. In experimental models of diabetes, decreased calcium sensitivity has been demonstrated in various ... -
Effect of diabetes on histamine-induced gastric acid secretion in the rat
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Effect of Insulin on the Decreased Beta-Adrenergic Responses of Duodenum and Atrium Isolated From Streptozotocin Diabetic Rats
Öztürk, Yusuf; Yıldızoğulları, N; Altan, Vecdi Melih; Özçelikay, At (Pergamon-Elsevier Science LTD, 1993)1. Decreased beta-adrenergic responses have been reported in both gastro-intestinal tract and atrium of experimentally-induced diabetic rats. The present study was undertaken to investigate in vitro effects of insulin on ... -
Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats
1. 1. Decreased ß-adrenergic and serotonergic responses have been reported in gastro-intestinal tract of experimentally diabetic rats. Effects of lithium on the decreased ß-adrenergic and serotonergic responsiveness of the ... -
Effect of Short and Long-Term Streptozotocin Diabetes on Smooth-Muscle Calmodulin Levels in the Rat
Öztürk, Yusuf; Aydın, Süleyman; Altan, Vecdi Melih; Yıldızoğlu-Arı, Nuray; Özçelikay, At (Churchill Livingstone, 1994)Diabetes mellitus is a metabolic disease associated with certain complications which have also been demonstrated in the experimental models of this disease. Altered responses to several agonists have been reported in various ... -
The Effect of Vanadate on Alloxan-Diabetic Rat Atria
Özçelikay, At; Yıldızoğulları, N; Özüarı, A; Öztürk, Yusuf; Altan, Vecdi Melih (Elsevier Sci Ireland LTD, 1993)In this study, we examined the effect of vanadate treatment on cardiac changes recognized in diabetic rats. In addition, the possible contribution of thyroid hormones to vanadate's effect on alloxan-diabetic atria was also ... -
The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats
Özçelikay, A. T.; Pekiner, C.; Arı, N.; Öztürk, Yusuf; ÖzüArı, A.; Altan, Vecdi Melih (Springer-Verlag, 1994)Vanadyl sulphate has been demonstrated to possess insulin-like effects in streptozotocin (STZ) diabetic rats, including the normalization of hyperglycaemia and the prevention of diabetes-induced cardiac dysfunction. However, ... -
Effects of experimental diabetes and insulin on smooth muscle functions
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The Effects of Glyburide and Insulin on the Cardiac-Performance in Rats With Non-Insulin-Dependent Diabetes-Mellitus
Özüarı, A; Öztürk, Yusuf; Yıldızoğulları, N; Özçelikay, At; Altan, Vecdi Melih (Pergamon-Elsevier Science LTD, 1993)1. The effects Of glyburide were studied on the myocardial contractile force and heart rate in the atria isolated from non-diabetic and non-insulin-dependent diabetic rats (diabetic). 2. In order to examine the myocardial ...