Browsing by Author "Ayhanci, Adnan"
Now showing items 1-4 of 4
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A comparative study on the therapeutic effects of Silymarin and Silymarin-Loaded Solid Lipid Nanoparticles on D-GaIN/TNF-alpha-induced Liver Damage in Balb/c Mice
Cengiz, Mustafa; Kutlu, Hatice Mehtap; Burukoğlu, Dilek; Ayhanci, Adnan (Pergamon-Elsevier Science LTD, 2015)Nanostructure-mediated drug delivery is known to have a potential to improve drug bioavailability, apart from fostering release deviation of drug molecules and enabling precision drug targeting. Solid lipid nanoparticles ... -
Potential Recruiting and Hepatoprotective Effects of Ellagic Acid in D-Galactosamine-Induced Liver Damage in Rats
Cengiz, Mustafa; Ali, Jama Hussein; Kutlu, Hatice Mehtap; Vejselova, Djanan; Ayhanci, Adnan (Zoological Soc Pakistan, 2017)The present study aims to investigate the therapeutic and protective effects of ellagic acid (EA) on the toxicity of the liver induced by D-Galactosamine (D-GaIN) in rats. With this in mind, the rats were categorized into ... -
Potential therapeutic effects of silymarin and silymarin-loaded solid lipid nanoparticles on experimental kidney damage in BALB/c mice: biochemical and histopathological evaluation
Cengiz, Mustafa; Ayhanci, Adnan; Kutlu, Hatice Mehtap; Musmul, Ahmet (Tubitak Scientific & Technical Research Council Turkey, 2016)Silymarin (Sm) is widely used in treating diseases that affect organs such as the liver, kidney, and gallbladder thanks to its antioxidative, renoprotective, antihepatotoxic, and anticarcinogenic properties. However, this ... -
Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats
Ayhanci, Adnan; Cengiz, Mustafa; Kutlu, Hatice Mehtap; Vejselova, Djanan (Springer, 2016)d-Galactosamine (d-GalN), which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. d-GalN intoxication also induces renal dysfunction ...