Yazar "Başaran, Ebru" için listeleme
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Chitosan nanoparticles for ocular delivery of cyclosporine A
Başaran, Ebru; Yenilmez, Evrim; Berkman, Murat Sami; Büyükköroğlu, Gülay; Yazan, Yasemin (Taylor & Francis LTD, 2014)In the present study, cyclosporine A (CsA) was successfully incorporated into cationic chitosan nanoparticles by spray-drying method aiming ocular application. Physicochemical characterisation of particles was performed ... -
Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
Başaran, Ebru; Demirel, Müzeyyen; Sırmagül, Başar; Yazan, Yasemin (Taylor & Francis LTD, 2010)In the present study, Cyclosporine A (CsA) was successfully incorporated into cationic solid lipid nanoparticles (SLN) for ocular application. Physicochemical characterizations of SLNs were analysed in detail during the ... -
Development of paclitaxel-loaded liposomal systems with anti-her2 antibody for targeted therapy
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Gezgin, Seval (Pharmacotherapy Group, 2016)Purpose: To develop liposome formulations containing monoclonal antibody anti-HER2 (MabHer2), and Paclitaxel (PTX). Methods: Seven different liposomal systems containing PTX, or MabHer2 or a combination of PTX and MabHer2 ... -
Epilepsi tedavisinde kullanılmak üzere yeni ilaç taşıyıcı sistemlerin formülasyonu çalışmaları
Başaran, Ebru; Anadolu Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Teknolojisi Anabilim Dalı; Aykaç, Kadir (Anadolu Üniversitesi - Sağlık Bilimleri Enstitüsü, 2020)Özeti: Epilepsi, beynin çeşitli bölgelerinde sinirsel iletimin aksaklığa uğraması sonucunda meydana gelen ve hastada dalgın bakış, istemsiz mimikler, kasılmalar, anlamsız konuşmalar, tekrarlayan hareketler ve bilinç kaybı ... -
Formulation and in vitro-in vivo evaluation of rosuvastatin calcium incorporated cyclodextrin, solid lipid and chitosan based drug delivery system
Al-Heibshy, Fawaz Nasser Shekh (Anadolu Üniversitesi, 2017)Kardiyovasküler rahatsızlıklar dünya çapında ölüm nedenlerinin ilk sırasında yer almaktadır. Kardiyovasküler rahatsızlıkların tedavisinde kullanılan pek çok etkin madde, sudaki düşük çözünürlükleri nedeni ile düşük ... -
Ocular application of chitosan
Başaran, Ebru; Yazan, Yasemin (Taylor & Francis LTD, 2012)Introduction: A major problem in ocular therapeutics with classical formulations is the maintenance of an effective drug concentration at the site of action for a long period of time. Enhancement of ocular bioavailability ... -
Ocular Application of Dirithromycin Incorporated Polymeric Nanoparticles: an In Vitro Evaluation
Başaran, Ebru (Turkish Pharmacists Assoc, 2017)Objectives: Ocular drug delivery is a difficult challenge especially with topical intillation which results in rapid drainage and non-productive drug absorption. For the improvement of the pre-corneal retention time and ... -
Ornidazole Incorporated Chitosan Nanoparticles for Ocular Application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Ornidazole incorporated chitosan nanoparticles for ocular application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Polymeric Cyclosporine-A Nanoparticles for Ocular Application
Başaran, Ebru; Demirel, Müzeyyen; Sırmagül, Başar; Yazan, Yasemin (Amer Scientific Publishers, 2011)In the present study, cyclosporine A (CsA) was incorporated successfully into cationic Eudragit(R) RS 100 nanoparticles (EPNs) aiming ocular application. Physicochemical characterization of the EPNs prepared was performed ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
Kırımlıoğlu, Gülsel Yurtdaş; Yenilmez, Evrim; Başaran, Ebru; Yazan, Yasemin (İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Preparation and in vitro evaluation of vaginal formulations including siRNA and paclitaxel-loaded SLNs for cervical cancer
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Yenilmez, Evrim; Yazan, Yasemin (Elsevier Science BV, 2016)Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic ... -
Preparation, Characterization and In Vitro Evaluation of Dirithromycin Loaded Eudragit (R) RS 100 Nanoparticles for Topical Application
Yenilmez, Evrim; Kırımlıoğlu, Gülsel Yurtdaş; Şenel, Behiye; Başaran, Ebru (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The purpose of the study was to formulate dirithromycin (DR) loaded Eudragit (R) RS 100 (ERS) nanoparticles for topical application and to analyze the physical and chemical characteristics and in vitro toxicity of the ... -
Preparation, characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated cyclodextrin-polyanhydride nanoparticles
Al-Heibshy, Fawaz N. S.; Başaran, Ebru; Arslan, Rana; Öztürk, Naile; Vural, İmran; Demirel, Müzeyyen (Taylor & Francis LTD, 2019)Objective: The aim of the study was to formulate, cyclodextrin (CD)-polyanhydride (PA) nanoparticles (CPNs) with rosuvastatin calcium (RCa) in order to enhance the poor oral bioavailability. Methods: CPNs containing RCa/CD ... -
Studies on rosuvastatin calcium incorporated chitosan salt nanoparticles
Al-Heibshy, Fawaz N. S.; Başaran, Ebru; Demirel, Müzeyyen (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2016)Cardiovascular diseases are the leading causes of death worldwide and rosuvastatin calcium (RCa) is one of the most effective drugs used for the prevention of coronary heart diseases. Considering low aqueous solubility ... -
Studies on Rosuvastatin Calcium Incorporated Chitosan Salt Nanoparticles
Al-Heibshy, Fawaz N. S.; Başaran, Ebru; Demirel, Müzeyyen (Colegio Farmaceuticos Provincia De Buenos Aires, 2016)Cardiovascular diseases are the leading causes of death worldwide and rosuvastatin calcium (RCa) is one of the most effective drugs used for the prevention of coronary heart diseases. Considering low aqueous solubility ... -
Voriconazole Incorporated Polymeric Nanoparticles for Ocular Application
Başaran, Ebru; Gencer, Hülya Karaca; Yenilmez, Evrim; Güven, Umay M. (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Limitations of topical ocular application lead to unsufficient treatment in severe ocular disorders, therefore the researchers focused on novel drug delivery systems for the achievement of enhanced ocular bioavailability. ... -
Voriconazole incorporated polymeric nanoparticles for ocular application
Başaran, Ebru; Karaca Gencer, Hülya; Yenilmez, Evrim; Güven, Umay Merve (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Limitations of topical ocular application lead to unsufficient treatment in severe ocular disorders, therefore the researchers focused on novel drug delivery systems for the achievement of enhanced ocular bioavailability. ...
