Yazar "Benkli, Kadriye" için listeleme
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Alfa-pinen'den Alfa-terpineol eldesi
Benkli, Kadriye (Anadolu Üniversitesi, 1990)Alfa-Terpineol parfüm endüstrisinde ve diğer yaygın uçucu kimya- sal maddelerin yapımında değerli bir ara üründür. Bu bileşiğin birkaç yolla hazırlandığı bilinmektedir. Terpenik alkoller normalde, terpenik olefinlere, ... -
Anti-lung Cancer and Anti-angiogenic Activities of New Designed Boronated Phenylalanine Metal Complexes
Varol, Mehmet; Koparal, Ayşe Tansu; Benkli, Kadriye; Bostancıoğlu, Rakibe Beklem (Bentham Science Publ LTD, 2018)Background: Drug design and discovery studies still remain of great importance in the search for more convenient chemotherapeutic to avoid the drug resistance, systemic toxicity or the long-term side effects. Objective: A ... -
Antibacterial and antifungal activities of some trimethoprim salts
Tunalı, Yağmur; Karaca, Hülya; İşcan, Gökalp; Demirci, Fatih; Benkli, Kadriye (Birkhauser Boston Inc, 2012)In this study, the antimicrobial activities of Trimethoprim (1), Trimethoprim + Maleic acid (2), Trimethoprim + Oxalic acid dihydrate (3), and Trimethoprim + trans-1,2-Cyclohexanedicarboxylic acid (4) were investigated for ... -
Apoptotic effects of dipyrido [3,2-a:2 ',3 '-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats
Tekin, Neslihan; Üstüner, Mehmet C.; Akyüz, Fahrettin; Özbayer, Cansu S.; Aydın, Özlem; Benkli, Kadriye; Özden, Hilmi (Springer, 2014)We evaluated the effects of dipyrido [3,2-a:2',3'-c] phenazine (dppz) Au(III) complex ([Au(dppz)Cl-2]Cl) on apoptosis during chemically induced hepatocellular carcinoma. 48 male Spraque-Dawley rats were divided into six ... -
Assessment of in vitro cytotoxic and genotoxic activities of some trimethoprim conjugates
Bayulken, Devrim Güzel; Bostancıoğlu, Rakibe Beklem; Koparal, Ayşe Tansu; Tüylü, Berrin; Dağ, Aydan; Benkli, Kadriye (Springer, 2018)Trimethoprim, a commonly used antibacterial agent, is widely applied in the treatment of variety of infections in human. A few studies have demonstrated an extensive exposure of man to antibiotics, but there is still a ... -
Bazı 3-Arilamino-5-ariloksimetil [1,2,4] triazol türevlerinin sentezi ve antimikrobiyal etkilerinin araştırılması
Benkli, Kadriye (Anadolu Üniversitesi, 1996)Bu çalışmada, otuzdört yeni 3-arilamino-5-ariloksimetil [1,2,4] triazol türevi bileşik, S-Metilarilizotiyoüronyum iyodür türevlerinin piridin içerisinde uygun fenoksiasetilhidrazidleriyle ısıtılması sonucunda sentezlenmiştir. ... -
Bazı 4-dihidroksiboril-dl-fenilalanin türevlerinin Au(III) ve Pt(II) komplekslerinin sitotoksik, anjiyogenik ve antianjiyogenik etkileri üzerine çalışmalar
Dönmez, Tamer (Anadolu Üniversitesi, 2011)Kanser tedavisinde, kemoterapi sıklıkla başvurulan bir yöntemdir. Proteinlerin ve enzimlerin pek çoğunun biyolojik aktivitesinin bu yapıların metal merkezlerine bağlı olduğu görüşünden hareketle pek çok metal kompleksi ... -
Biological activities of Cu(II) and Hg(II) complexes of a heptadentate Schiff base ligand
Ergene, Emel; Sivas, Hülya; Benkli, Kadriye (Tubitak Scientific & Technical Research Council Turkey, 2010)Two metal complexes were synthesized as [Hg(L)](ClO4)(2) and [Cu(L)](ClO4), by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of Hg(II) and ... -
Cytotoxic and genotoxic effects of [Ru(phi)(3)](2+) evaluated by Ames/Salmonella and MTT methods
Benkli, Kadriye; Tunalı, Yağmur; Cantürk, Zerrin; Artagan, öge; Alanyali, Filiz (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In this work, we synthesized and evaluated the cytotoxic effect of [Ru(phi)(3)](2+), on rat C6 glioma cell line. Cell viability was determined by assay with 3-(4-5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide ... -
Design and synthesis of novel organometallic complexes using boronated phenylalanine derivatives as potential anticancer agents
Varol, Mehmet; Benkli, Kadriye; Koparal, Ayşe Tansu; Bostancıoğlu, Rakibe Beklem (Taylor & Francis LTD, 2019)Drug design and discovery studies are important because of the prevalence of diseases without available medical cures. New anticancer agents are particularly urgent because of the high mortality rate associated with cancer. ... -
Designing of the new antithrombotic and also anticancer gold complexes
Benkli, Kadriye (Pergamon-Elsevier Science LTD, 2016)… -
The effects of some phenanthroline ruthenium (II) complexes on a549 cell proliferation
Ruthenium (II) komplekslerinin DNA bağlanması He ilgili olan yüksek antitumor aktiviteleri nedeni He bu bileşikler son yıllarda araştırmacıların yoğun ilgisini çekmektedir. Bu çalismada imidazo[4,5-f][ 1,10]fenantrolin ... -
The effects of some phenanthroline ruthenium (II) complexes on A549 cell proliferation [Bazi{dotless} fenantrolin rutenyum (II) komplekslerinin a549 hücre çogalmasi{dotless} üzerine etkileri]
In recent years, ruthenium (II) complexes have increasingly attracted the interest of researchers because of their high antitumor activities that are usually related to DNA binding. Here, we synthesized two ruthenium (II) ... -
Evaluation of hearing impaired and normal hearing students’ reading miscues by miscue analysis
Okuma hataları, okuyucunun dilin ipucu sistemleri ile metni anlamada kullandığı okuma stratejileri hakkında bilgi vermektedir. Bu çalışmanın amacı, koklear implantlı öğrenciler ile işiten öğrencilerin öykülerdeki okuma ... -
Gold(III) compounds-mediated inhibition of lung cancer cell proliferation
Bostancıoğlu, R. Beklem; Kaya, Murat; Koparal, Ayşe Tansu; Benkli, Kadriye (Lippincott Williams & Wilkins, 2016)Research on chemotherapeutics for lung cancer is crucial for designing a new therapeutic strategy against malignant lung tumors. Although radiotherapy and chemotherapy, which are not selective for cancer cells and exert ... -
The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line
Kaplan, Ayşe; Benkli, Kadriye; Koparal, Ayşe Tansu (Springer, 2018)Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat ... -
Inhibition of C6 Glioma Cell Proliferation by Au(III) and Pt(II) Complexes of 1,10-Phenanthroline-5,6-dione
Dikmen, Miriş; Benkli, Kadriye; Öztürk, Yusuf (Asian Journal Of Chemistry, 2011)In this study, we studied the antiproliferative effecs of Au(III) and Pt(II) metal complexes of 1,10-phenanthroline-5,6-dione and cisplatin on rat glioma C6 cells. The antiproliferative effects were evaluated by MTT ... -
Investigation of Genotoxic Effects of Some Ruthenium Complexes According to Cis-platinum
Alanyalı, Feriştah; Ergin, E.; Artagan, Oge; Benkli, Kadriye (Asian Network Scientific Information-Ansinet, 2011)The aim of our study was, to synthesize and evaluate the mutagenicity of Ruthenium complexes, on Salmonella strains of TA100 and TA98 by Ames Test. [Ru(L)(2)(B)Pt] Cl-2 complexes were synthesized using 1, 10-phenanthroli ...
