Yazar "Biltekin, Sevde N." için listeleme
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Potent ribonucleotide reductase inhibitors: Thiazole-containing thiosemicarbazone derivatives
Ertas, Merve; Sahin, Zafer; Bulbul, Emre F.; Bender, Ceysu; Biltekin, Sevde N.; Berk, Barkin; Demirayak, Seref (Wiley-V C H Verlag Gmbh, 2019)The antioxidant, antimalarial, antibacterial, and antitumor activities of thiosemicarbazones have made this class of compounds important for medicinal chemists. in addition, thiosemicarbazones are among the most potent and ... -
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
Ertaş, Merve; Şahin, Zafer; Berk, Barkın; Yurttaş, Leyla; Biltekin, Sevde N.; Demirayak, Şeref (Wiley-V C H Verlag GMBH, 2018)Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ... -
Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors
Şahin, Zafer; Ertaş, Merve; Bender, Ceysu; Bülbül, Emre F.; Berk, Barkin; Biltekin, Sevde N.; Demirayak, Şeref (Wiley, 2018)Hit, Lead & Candidate Discovery After acetylcholine is released into the synaptic cleft, it is reabsorbed or deactivated by acetylcholinesterase (AChE). Studies on Alzheimer's disease (AD) in the mid-20th century proved ...
