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Novel thiazole-piperazine derivatives as potential cholinesterase inhibitors
Demirayak, Seref; Sahin, Zafer; Ertas, Merve; Bulbul, Emre Fatih; Bender, Ceysu; Biltekin, Sevde Nur; Yurttas, Leyla (Wiley, 9999)Dementia is a cognitive disorder mostly associated with Alzheimer's disease (AD) in addition to being seen in many other diseases of the central nervous system (CNS). the limited number of drugs is not sufficient to provide ... -
Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives
Şahin, Zafer; Ertaş, Merve; Berk, Barkın; Biltekin, Sevde Nur; Yurttaş, Leyla; Demirayak, Şeref (Pergamon-Elsevier Science LTD, 2018)Steroidal and non-steroidal aromatase inhibitors target the suppression of estrogen biosynthesis in the treatment of breast cancer. Researchers have increasingly focused on developing non-steroidal derivatives for their ...
