Yazar "Can, Nafiz Öncü" için listeleme
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Akrilamid'in analitik yöntemler kullanılarak analizi ve gıdalardaki tayini
Can, Nafiz Öncü; Anadolu Üniversitesi, Sağlık Bilimleri Enstitüsü; Işıkdağ, Müjde Aslı (Tez (doktora) - Anadolu Üniversitesi, 2018)Bu çalışmada dönüşümlü voltametri çalışmaları sonucunda akrilamidin indirgenme reaksiyonunun tersinmez ve difüzyon kontrollü olduğunu göstermiştir. Bu amaçla Osteryoung Kare Dalga Voltametrisi yöntemi kullanılarak yürütülen ... -
Akrilamidin gıda maddelerinde oluşumuna etki eden faktörlerin incelenmesi ve miktarının tayini
Can, Nafiz Öncü (Anadolu Üniversitesi, 2007)Akrilamid patates cipsleri, bisküvi ve kahve gibi çeşitli gıda maddelerinde sıklıkla bulunan, sıcaklıkla oluşan gıda zehirlerinden biridir. Akrilamidin bazı nörotoksik ve karsinojenik etkiler gösterdiği ispatlanmış ve ... -
Analysis of Acrylamide in Traditional and Nontraditional Foods in Turkey Using Hplc-Dad With Spe Cleanup
Can, Nafiz Öncü; Arli, Göksel (Taylor & Francis Inc, 2014)Acrylamide is a heat-generated food toxicant, which exists in various foodstuffs such as potato chips, biscuits, and coffee. It has been demonstrated that acrylamide possesses some neurotoxic and carcinogenic effects and ... -
Comparative study of different chemistries and particle properties, high-performance liquid chromatography stationary phases in separation of escitalopram oxalate and its impurities in different pharmaceutical dosage forms
Badulla, Wafa; Can, Nafiz Öncü; Atkoşar, Zeki; Arli, Göksel; Aboul-Enein, Hassan Y. (Wiley-V C H Verlag GMBH, 2019)The liquid chromatographic separation performance of 12 different columns was evaluated for the estimation of the escitalopram oxalate and six of its impurities in different pharmaceutical formulations. All columns exhibited ... -
Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors
Can, Nafiz Öncü; Osmaniye, Derya; Levent, Serkan; Sağlık, Begüm Nurpelin; Korkut, Büşra; Atlı Eklioğlu, Özlem; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)In the recent works, it was shown that numerous thiazolylhydrazine derivatives display hMAO inhibitory activity in the range of micromolar concentration. Hence, in the present study a new series of new thiazole-hydrazines ... -
Determination of amoxicillin by flow injection analysis using UV-detection, potentiometry, and conductometry in pharmaceutical preparations
Altıokka, Göksel; Can, Nafiz Öncü; Aboul-Enein, Hassan Y. (Taylor & Francis Inc, 2007)A method for direct determination of amoxicillin in pharmaceuticals using flow injection analysis (FIA) with UV detection adjusted at 228 nm, along with potentiometer and condoptometric methods are described. The best ... -
Determination of azapropazone in its pharmaceutical form by HPLC and flow injection analysis
Can, Nafiz Öncü; Altıokka, Göksel (Taylor & Francis Inc, 2005)Azapropazone is an analgesic and anti-inflammatory agent that is used in the treatment of musculoskeletal and joint disorders, as well as in acute gout, because of its uricosuric properties. A simple and sensitive high ... -
Determination of cefuroxime axetil in tablets and biological fluids using liquid chromatography and flow injection analysis
Can, Nafiz Öncü; Altıokka, Göksel; Aboul-Enein, Hassan Y. (Elsevier Science BV, 2006)Cefuroxime axetil is the pro-drug of cephalosporin cefuroxime that is used in the treatment of common community-acquired infections. A simple and precise liquid chromatographic method for the determination of cefuroxime ... -
The determination of levofloxacin by flow injection analysis using UV detection, potentiometry, and conductometry in pharmaceutical preparations
Altıokka, Göksel; Atkoşar, Zeki; Can, Nafiz Öncü (Pergamon-Elsevier Science LTD, 2002)A flow injection analysis (FIA) using UV detection, potentiometry and conductometry for levofloxacin (LVF) are described in this study. The best solvent system was found to consist of 0.2 V acetate buffer at pH 3 having ... -
Determination of nabumetone in pharmaceutical formulation by flow injection analysis (FIA) with UV-detection
Can, Nafiz Öncü; Tuncel, M; Aboul-Enein, Hassan Y. (Govi-Verlag GMBH, 2003)A precise and accurate FIA method for the quantification of nabumetone (NAB) in pharmaceuticals is described. The best suitable carrier solvent system consisted of ethanol: water (30: 70 v/v). Sample solution (4.7 x 10(-6) ... -
Determination of Ochratoxin A in Turkish Wines
Altıokka, Göksel; Can, Nafiz Öncü; Atkoşar, Zeki; Aboul-Enein, Hassan Y. (Food & Drug Adminstration, 2009)A validated, simple and highly sensitive analytical method was described for the determination of Ochratoxin A (OTA) in various wines produced in Turkey. OTA concentrations of 25 wine samples were examined using high ... -
Determination of piribedil in human serum, urine and pharmaceutical dosage form by LC-DAD
Altıokka, Göksel; Can, Nafiz Öncü; Aboul-Enein, Hassan Y. (Springer Heidelberg, 2008)A rapid, selective and sensitive reversed-phase liquid chromatographic (LC) method was developed for the determination of piribedil in human serum, urine and pharmaceutical dosage form. LC analysis was carried out using ... -
Determination of Ticlopidine in Pharmaceutical Tablets by Flow Injection Analysis Using UV-Detection
Can, Nafiz Öncü; Altıokka, Göksel; Aboul-Enein, Hassan Y. (Taylor & Francis Inc, 2008)A precise and accurate flow injection analysis method for the quantification of ticlopidine in pharmaceuticals is described. An aqueous carrier stream, which was entirely prepared with water was chosen for the flow injection ... -
Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF
Can, Nafiz Öncü (MDPI, 2018)Avanafil (AVA), one of the most effective drugs prescribed for erectile dysfunction, is a pyrimidine-derivative PDE5 inhibitor. In the current work, new LC methods were developed and validated for quantitative determination ... -
Farmasötik preparatlardaki deksketoprofenin tayini için yeni bir sıvı kromatografisi yönteminin geliştirilmesi
Zitouni, Kim. Aylin Ece (Anadolu Üniversitesi, 2018)Piyasada çeşitli farmasötik formları bulunan ve nonsteroidal antienflamatuvar ilaçlar grubuna ait olan deksketoprofen ağrı kesici olarak kullanılan bir maddedir. Antienflamatuvar etkisi dışında analjezik, antipiretik ve ... -
HPLC determination of cefprozil in tablets using monolithic and C-18 silica columns
Can, Nafiz Öncü (Wiley-V C H Verlag GMBH, 2011)Cefprozil (CPZ) is a second-generation semi-synthetic cephalosporin antibiotic that commonly exists as the mixture of Z and E diastereoisomers, at the ratio of approximately 9:1. A novel reversed-phase HPLC method for the ... -
Investigating the Antidepressant-like Effects of some Benzimidazolepiperidine Derivatives by In-Vivo Experimental Methods
Turan, Nazlı; Özkay, Ümide Demir; Can, Nafiz Öncü; Can, Özgür Devrim (Bentham Science Publ LTD, 2019)Background: Benzimidazole and piperidine rings are important pharmacophore groups for drug design studies. Objective: In this study, we aimed to investigate the antidepressant-like activity of some 2-(4- substituted-phen ... -
Investigation of monoamine oxidase inhibitory activities of new chalcone derivatives
Can, Nafiz Öncü (Çukurova University, Fac Medicine, 2018)Purpose: In the present study, it is aimed to investigate monoamine oxidase (MAO) enzyme inhibition potencies of some new chalcone derivatives. Materials and Methods: Nine novel chalcone derivatives were synthesized and ... -
İşlenmiş gıdaların lezzetini değiştirmek için kullanılan bazı katkı maddelerinin eşzamanlı analizi
Sezgin, Burcu (Anadolu Üniversitesi, 2016)Değişen yaşam şartları ve gelişen teknolojiye bağlı olarak, gıda ve farmasötik ürünlerde çok çeşitli katkı maddeleri kullanılmaktadır. Özellikle gıda güvenliğine verilen önemin artması ve katkı maddelerinin kullanımındaki ...
