Yazar "Cantürk, Zerrin" için listeleme
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Alfa humulenin SH-SY5Y hücre hattı üzerinde oluşturulmuş in vitro ko-kültür modelinde antiproliferatif antiapoptotik ve nöroprotektif etkilerinin araştırılması
Cantürk, Zerrin; Anadolu Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Mikrobiyoloji Anabilim Dalı; Tuncer, Perihan Ezgi (Anadolu Üniversitesi, 2021)Latince ismi ile Humulus Lupulus’un şetbetçiotu bitkisinin majör etken maddesi olan Alfa Humulen, üç eşlenmemiş C=C çift bağ içeren üç izopren biriminden oluşan monosiklik bir seskiterpendir. Şerbetçiotundan başka kenevir, ... -
Antiangiogenic and antiproliferative effects of halotolerant Penicillium chrysogenum var. chrysogenum on the human umbilical vein endothelial cells (HUVECs)
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Demirtaş, Buket; İlhan, Semra (IEEE, 2013)Inhibitors of angiogenesis have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. In this study was to investigate the ... -
Anticancer Effects of Secondary Metabolites of Penicillium Chrysogenum Var. Chrysogenum on Colon Adenocarcinoma Cells
Cantürk, Zerrin; Artagan, Öge; Dilunen, Miris (Parlar Scientific Publications (PSP), 2016)Aim of this study was to investigate the antioxidant activity, cytotoxicity and antiproliferative effects of ethyl acetate extract of Penicillium chrysogenum var. chrysogenum (hPc.var.c) on the Caco-2 cells. hPc.var.c ... -
Antimicrobial and Cytotoxic Evaluation of New Quinazoline Derivatives
Turan, Gülhan; Yurttaş, Leyla; Saka, Güner; Cantürk, Zerrin; Karaca Gencer, Hülya; Baysal, Merve; Kaplancıklı, Zafer Asım (Natural Products Inc, 2016)The synthesis of nine new quinazoline derivatives (2a-21) and evaluation of their antimicrobial and cytotoxic activities were aims of the present work. For the synthesis of the compounds, 2-chloro-6,7-dimethoxyquinazolin-4-amine ... -
Antioxidant properties of halotolerant Penicillium chrysogenum var. chrysogenum secondary metabolites
Cantürk, Zerrin; Dikmen, Miriş; Öztürk, Nilgün; Kocabiyik, Ercin; İlhan, Semra (IEEE, 2013)In this study it was aimed at evaluating antioxidant potential of Penicillium sp. broth filtrate and extract. In our study we examined broth filtrate DPPH and free radical scavenging activity, and also total phenol content ... -
Antioxidant, Antiproliferative and Apoptotic Effects of Secondary Metabolites of Halotolerant Aspergillus terreus on Colon Adenocarcinoma Caco-2 Cells
Dikmen, Miriş; Cantürk, Zerrin; Artagan, Oge; Öztürk, Nilgün (Asian Network Scientific Information-Ansinet, 2017)Objective: This study aimed to investigate the antioxidant and anticancer effects of the secondary metabolites of halotolerant Aspergillus terreus-2 (hAt-2) on colon adenocarcinoma (Caco-2) cells. The hAt-2 was isolated ... -
Compared effects of azole antifungals on cytokine production of THP-1 cells activated by Candida albicans
Cantürk, Zerrin (Marmara University, Fac Medicine, 2016)In this study we compared the cytotoxic and proinflammatory/antiinflammatory effects of azole antifungals such as clotrimazole, ketoconazole, miconazole and fluconazole on Candida albicans co-culture with THP-1 cell line. ... -
Cytotoxic and apoptotic effects of boron compounds on leukemia cell line
Cantürk, Zerrin; Tunalı, Yağmur; Korkmaz, Seval; Gülbas, Zafer (Springer, 2016)In this study we investigated the effects of boric acid and sodium tetraborate on an acute leukemia cell line and healthy human lymphocytes. We evaluated the effects of boric acid and sodium tetraborate on the HL-60 cell ... -
Cytotoxic and genotoxic effects of [Ru(phi)(3)](2+) evaluated by Ames/Salmonella and MTT methods
Benkli, Kadriye; Tunalı, Yağmur; Cantürk, Zerrin; Artagan, öge; Alanyali, Filiz (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In this work, we synthesized and evaluated the cytotoxic effect of [Ru(phi)(3)](2+), on rat C6 glioma cell line. Cell viability was determined by assay with 3-(4-5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide ... -
Cytotoxic Effects of Resveratrol, Rutin and Rosmarinic Acid on ARH-77 Human (Multiple Myeloma) Cell Line
Cantürk, Zerrin; Dikmen, Miriş; Artagan, Oge; Özarda, Mustafa Güçlü; Öztürk, Nilgün (Natural Products Inc, 2016)Multiple myeloma (MM) cancers are 10% of hematological cancers. Leukemia ARH-77 is' a malignancy like MM with a worse course of disease and the survival rate from it is very low. Therefore, ARH-77 is a commonly used model ... -
Determining antioxidant properties of halotolerant microfungi
Kaya, Ayla; Cantürk, Zerrin; Kocabiyik, E.; İlhan, Semra (Wiley-Blackwell, 2011)… -
Escitalopram oxalate, a selective serotonin reuptake inhibitor, exhibits cytotoxic and apoptotic effects in glioma C6 cells
Dikmen, Miriş; Cantürk, Zerrin; Öztürk, Yusuf (Cambridge University Press, 2011)Objective: Various antidepressants, mainly tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), have been reported to exhibit potent anticancer properties in different cancer cells. In this ... -
Evaluation of Antiangiogenic and Antimetastatic Effects of Penicillium chrysogenum Secondary Metabolites
Dikmen, Miriş; Cantürk, Zerrin; Tilki, E. Kaya; EnGür, Selin (Medknow Publications & Media Pvt LTD, 2017)Development of resistance to standard therapy and toxic side effects are the major challenges encountered in chemotherapy of colorectal cancer. Increasing evidence has shown the ability of natural products to overcome ... -
Evaluation of Antimicrobial Effect against Some Microorganisms and Apoptotic Activity against Candida Species of New Vanillin Derivatives
Ünver, Hakan; Cantürk, Zerrin; Özarda, M. Güçlü (2019)Eleven vanillin derivatives was synthesized, characterized successfully and their antibacterial and anticandidal properties were investigated on seven bacterial species and four candida species. These bacterial species are ... -
Evaluation of Antioxidant and Antiproliferative Metabolites of Penicillium flavigenum Isolated from Hypersaline Environment: Tuz (Salt) Lake by Xcelligence Technology
Cantürk, Zerrin; Kocabiyik, E.; Öztürk, Nilgün; İlhan, Semra (Maik Nauka/Interperiodica/Springer, 2017)The aim of the study is the determination of antioxidant and antiproliferative activities of fungal isolates' metabolites belonging to Penicillium flavigenum isolated from Lake Tuz, Turkey. Evaluation of the antioxidant ... -
Evaluation of synergistic anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans
Cantürk, Zerrin (Food & Drug Adminstration, 2018)This study aimed to investigate the synergy between anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans and Candida glabrata, with the help of a quantitative checkerboard microdilution ... -
Evaluation of the antileukemic effects of neurokinin-1 receptor antagonists, aprepitant, and L-733,060, in chronic and acute myeloid leukemic cells
Dikmen, Miriş; Gökhaner, Gökhan; Cantürk, Zerrin (Lippincott Williams & Wilkins, 2019)Neurokinin-1 receptor (NK1R) antagonists are known for their anxiolytic, antiemetic, anticancer, and antiinflammatory effects. Aprepitant is used in vomiting and nausea, which are the most common side-effects of patients ... -
Farklı mikrobiyal kaynaklı lipopolisakkaritlerle stimüle edilmiş monosit hücrelerinde Selonsertib'in (GS4997) immün yanıta etkisi
Cantürk, Zerrin; Anadolu Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Mikrobiyoloji Anabilim Dalı; Gündoğan, Fatma (2018)İnflamasyon, doku veya organın kendisine zarar verebilecek etkene karşı savaşması durumudur. İnflamasyonda önemli sitokinler; TNF-α, IL-1β'dır. İnflamasyonun tedavisinde; Nonsteroidal Antiinflamatuvar ilaçlar kullanılır. ...
