Yazar "Dikmen, Gökhan" için listeleme
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The Anticancer Activity of Complex [Cu-2(mu-(C6H5)(2)CHCOO)(3)(bipy)(2))](ClO4) -Solid Lipid Nanoparticles on MCF-7 Cells
Kani, İbrahim; Dikmen, Gökhan; Eskiler, Gamze Güney; Cecener, gülsah; Tunca, Berrin; Egeli, Ünal (Bentham Science Publ LTD, 2016)Recent studies have focused on the potential use of metal-based complexes for the treatment of cancer. However, there are some limitations of metal-based ligands for the treatment of cancer due to their toxic effects. In ... -
Bazı Boronik Asit Türevlerinin DFT, Raman, FT-IR ve NMR spektroskopik yöntemler ile teorik ve deneysel olarak incelenmesi
Dikmen, Gökhan (Anadolu Üniversitesi, 2016)2-flor-3-metil piridin-5-boronik asit, 6-brom-3-piridinil boronik asit, 4 karboksi-3-fenil boronik asit ve 3-akrilamido fenil boronik asit gibi bazı boronik asit türevlerine ait farklı moleküllerin en kararlı kimyasal ... -
Characterization of Solid Lipid Nanoparticles Containing Caffeic Acid and Determination of its Effects on MCF-7 Cells
Dikmen, Gökhan; Güney, Gamze; Genç, Lütfi (Bentham Science Publ LTD, 2015)Many anticancer drugs that are currently used in cancer treatment are natural products or their analogues by structural modification. Caffeic acid (3, 4-dihydroxycinnamic acid; CA) is classified as hydroxycinnamic acid and ... -
Effects of hydrochloric acid treatment on structure characteristics and C2H4 adsorption capacities of nye bentonite from Turkey: a combined FT-IR, XRD, XRF, TG/DTA and MAS NMR study
Erdoğan Alver, Burcu; Alver, Özgür; Günal, Aytaç; Dikmen, Gökhan (Springer, 2016)In this study, a bentonite sample from nye, Turkey was treated with various HCl solutions (0.1, 1.0 and 5.0 M) at 90 A degrees C during 3 and 6 h. X-ray diffraction (XRD), X-ray fluorescence (XRF), differential thermal ... -
Investigation of tautomeric behavior of 3-amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide using Fourier Transform infrared and nuclear magnetic resonance spectroscopic methods: A density functional theory supported study
Ertürk, Aliye Gediz; Gümüş, Sedat; Dikmen, Gökhan; Alver, Özgür (Elsevier Science BV, 2016)Sulfonamide derivatives have been widely incorporated in different types of studies, particularly in bioorganics and medicinal chemistry. Molecular conformation or tautomeric forms of molecules are directly related to their ... -
The Investigation of the Effect of Grain Size on Raman and 29si Mas NMR Spectra of Bentonites from Turkey
Bilim ve endüstri alanında killere oldukça yoğun bir ilgi vardır. Literatürde; titreşim spektroskopisi ve özellikle FT-IR ve NMR spektroskopik yöntemlerinin, killer üzerine olan bilimsel çalışmalarda sıklıkla kullanıldığı ... -
INVESTIGATION OF THE INFLUENCE OF HEAT TREATMENT ON THE STRUCTURAL PROPERTIES OF ILLITE-RICH CLAY MINERAL USING FT-IR, 29Si MAS NMR, TG AND DTA METHODS
In the production and development of building materials, fired clays are the center of major interest. They particularly play an important role in the building industry. Henceforth, in order to analyze the effect of heat ... -
An investigation onto the molecular structure of 5-chloro-3-(2-(4-ethylpiperazine-1-il)-2-oxoethyl)benzo[d]thiazole-2(3H)-on drug molecule before and after atmospheric pressure plasma treatment
Tanışlı, Murat; Tasal, Erol; Şahin, Neslihan; Dikmen, Gökhan (Elsevier Science BV, 2018)The spectra of molecular structure for the 5-chloro-3-(2-(4-ethylpiperazine-1-il)-2-oxoethyl)benzo[d]thiazole-2(3H)-on drug molecule (abbreviated as 5KEB) before and after the atmospheric pressure plasma treatments (APPTs) ... -
Katı Lipid Nanopartikül Formülasyonları İçindeki Nokodazol’ün Belirlenmesi için Onaylanmış HPLC Metodu
Dikmen, Gökhan; Genç, Lütfi; Şener, Erol (2014)Nokadazol (NCD), mikrotübüllerin polimerizasyonuyla etkileşerek hücre içinde etkisini gösteren anti neoplastik bir ajandır. NCD hücre iskeletini etkilediği için hücre biyoloji deneylerinde kontrol grubu olarak kullanılmaktadır. ... -
NMR determination of solvent dependent behavior and XRD structural properties of 4-carboxy phenylboronic acid: A DFT supported study
Dikmen, Gökhan; Alver, Özgür; Parlak, Cemal (Elsevier Science BV, 2018)Solvent dependent structural properties of 4-carboxy phenylboronic acid (4-cpba) were investigated by X-ray diffraction (XRD) and nuclear magnetic resonance (NMR) spectroscopic methods. The molecular structure and geometric ... -
NMR, FT-IR spectroscopic studies and molecular docking study of 4-acetoxyphenethyl acrylate
Dikmen, Gökhan; Alver, Özgür (World Scientific Publ Co Pte LTD, 2017)Conformational, structural, vibrational spectroscopic properties and nuclear magnetic chemical shift values of 4-acetoxyphenethyl acrylate (4APA) were investigated using spectroscopic and theoretical approaches including ... -
NMR, FT-IR, Raman and UV-Vis spectroscopic investigation and DFT study of 6-Bromo-3-Pyridinyl Boronic Acid
Dikmen, Gökhan; Alver, Özgür (Elsevier Science BV, 2015)Possible stable conformers and geometrical molecular structures of 6-Bromo-3-Pyridinyl Boronic acid (6B3PBA; C5H5BBrNO2) were studied experimentally and theoretically using FT-IR and Raman spectroscopic methods. FT-IR and ... -
Nokodazol yüklü katı lipid nanopartiküllerin hazırlanması ve karakterizasyonu
Dikmen, Gökhan (Anadolu Üniversitesi, 2012)Bu çalışma, nokodazol etken maddesinin katı lipid nanopartiküllere yüklenerek, bu KLN formülasyonlarına karakterizasyon çalışmaları yapılarak, KLN'lerin nokodazol maddesine göre daha iyi fiziksel ve kimyasal özelliklere ... -
Structural characterization, solvent effects on nuclear magnetic shielding tensors, experimental and theoretical DFT studies on the vibrational and NMR spectra of 3-(acrylamido)phenylboronic acid
Alver, Özgür; Kaya, Mehmet Fatih; Dikmen, Gökhan (Elsevier Science BV, 2015)Structural elucidation of 3-(acrylamido)phenylboronic acid (C9H10BNO3) was carried out with H-1, C-3 and HETCOR NMR techniques. Solvent effects on nuclear magnetic shielding tensors were examined with deuterated dimethyl ... -
Structure analysis and spectroscopic characterization of 2-Fluoro-3-Methylpyridine-5-Boronic Acid with experimental (FT-IR, Raman, NMR and XRD) techniques and quantum chemical calculations
Alver, Özgür; Dikmen, Gökhan (Elsevier Science BV, 2016)Possible stable conformers, geometrical molecular structures, vibrational properties as well as band assignments, nuclear magnetic shielding tensors of 2-Fluoro-3-Methylpyridine-5-Boronic Acid (2F3MP5BA) were studied ... -
Validated HPLC method for the determination of nocodazole in solid lipid nanoparticle formulations [Kati{dotless} lipid nanopartikül formiilasyonlan İindeki nokodazol'ün belirlenmesiiçin onaylanmiş HPLC metodu]
Dikmen, Gökhan; Genç, Lütfi; Şener, E. (Turkish Pharmacists Association, 2014)Nocodazole (NCD) is an anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. As NCD affects the cytoskeleton, it is often used incell biology experiments as a control. ... -
Vibrational spectroscopic investigation of methyl(5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl: A comparative density functional study
Alver, Özgür; Parlak, Cemal; Kaya, M. Fatih; Dikmen, Gökhan; Genç, Lütfi (Maik Nauka/Interperiodica/Springer, 2014)FT-IR and Raman spectra of methyl(5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl (nocodazole) are experimentally examined in the region of 4000-400 cm(-1). The optimized geometric parameters, conformational equilibria, normal ...
