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Synthesis of thiadiazole derivatives bearing hydrazone moieties and evaluation of their pharmacological effects on anxiety, depression, and nociception parameters in mice
Can, Özgür Devrim; Altıntop, Mehlika Dilek; Özkay, Ümide Demir; Ucel, Umut İrfan; Doğruer, Burge; Kaplancıklı, Zafer Asım (Pharmaceutical Soc Korea, 2012)Novel thiadiazole derivatives bearing hydrazone moieties were synthesized through the reaction of 2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio)]acetohydrazide with aldehydes/ketones. The chemical structures of the compounds ...