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Antiangiogenic and antiproliferative effects of halotolerant Penicillium chrysogenum var. chrysogenum on the human umbilical vein endothelial cells (HUVECs)
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Demirtaş, Buket; İlhan, Semra (IEEE, 2013)Inhibitors of angiogenesis have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. In this study was to investigate the ... -
Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells
Engür, Selin; Dikmen, Miriş; Öztürk, Yusuf (Taylor & Francis LTD, 2016)Inhibition of the proteasome has emerged as a clinically effective anticancer therapeutic approach in recent years. Bortezomib (Velcade (R)) showed extremely high potency against a wide range of cancer cell lines. Ixazomib ... -
The evaluation of the anti-cancer activity of ixazomib on Caco2 colon solid tumor cells, comparison with bortezomib
Engür, Selin; Dikmen, Miris (Taylor & Francis LTD, 2017)Proteasome inhibition has recently emerged as a clinically effective anticancer therapeutic approach. The first proteasome inhibitor, bortezomib (Velcade, PS-341), and new proteasome inhibitors including ixazomib have ... -
The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats
Bayramoğlu, Gökhan; Bayramoğlu, Ayşegül; Engür, Selin; Şentürk, Hakan; Öztürk, Nilgün; Çolak, Suat (Springer, 2014)Little is known about the effective role of Hypericum perforatum on hepatic ischemia-reperfusion (I/R) injury in rats. Hence, albino rats were subjected to 45 min of hepatic ischemia followed by 60 min of reperfusion period. ... -
Inhibitory effects of secondary metabolites of halotolerant aspergillus terreus on angiogenesis
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Kaya, Tilki, E. (Scientific Publishers of India, 2017)Angiogenesis inhibitors have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. Fungi have been known (as) a wide useful source ... -
Inhibitory effects of secondary metabolites of halotolerant Aspergillus terreus on angiogenesis.
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Tilki, Kaya E. (Allied Acad, 2017)Angiogenesis inhibitors have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. Fungi have been known (as) a wide useful source ... -
Neuritogenic Activity of Epigallocatechin Gallate and Curcumin Combination on Rat Adrenal Pheochromocytoma Cells
Dikmen, Miriş; Kaya-Tilki, Elif; Engür, Selin; Öztürk, Yusuf (Parlar Scientific Publications (PSP), 2017)Plant phytochemicals are important neuroprotective agents which mainly act as antioxidants by scavenging stress -induced free radicals in the brain. Phytochemicals from medicinal plants including epigallocatechin gallate ...
