Yazar "Erkasap, Nilüfer" için listeleme
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Antiproliferative and antiapoptotic effect of thymoquinone on cancer cells in vitro
Kuş, Gökhan; Özkurt, Mete; Kabadere, Selda; Erkasap, Nilüfer; Göğer, Gamze; Demirci, Fatih (Comenius University, 2018)OBJECTIVES: Nigella sativa oil and thymoquinone were comparatively tested in vitro for their effects on human cancer cell lines (glioma, T98; prostate, LnCaP) as well as mouse embryonic fi broblast cell lines (3T3), and ... -
Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia
Dernek, S; İkizler, M; Erkasap, Nilüfer; Ergün, B; Köken, T; Yılmaz, K; Kural, T (Taylor & Francis LTD, 2004)Objective-The major objective of the present study is to evaluate the potential role of resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the myocardium from the deleterious effects of ... -
Comparison of a ceramidase inhibitor (ceranib-2) with C2 ceramide and cisplatin on cytotoxicity and apoptosis of glioma cells
Kuş, Gökhan; Özkurt, Mete; Öztopçu Vatan, Pınar; Erkasap, Nilüfer; Uyar, Ruhi; Kabadere, Selda (Tubitak Scientific & Technical Research Council Turkey, 2018)Inhibiting ceramidase activity in cancer cells has been identified as a promising target for cancer therapy in recent studies. Thus, we examined the possible role of ceranib-2, a novel ceramidase inhibitor, on growth and ... -
Effect of alpha lipoic acid and silymarin on bladder outlet obstruction
Yıldırım, Abidin; Başesikoğlu, Barbaros; Temel, Halide Edip; Erkasap, Nilüfer; Yenilmez, Aydın; Uslu, Sema; Dönmez, Turgut (Spandidos Publ LTD, 2013)The aim of the present study was to determine whether the treatment of obstructed rat bladders with alpha lipoic acid (ALA) and silymarin reverses the biochemical and physiological responses to bladder outlet obstruction ... -
Effects of carvacrol on defects of ischemia-reperfusion in the rat liver
Canbek, Mediha; Uyanoğlu, Mustafa; Bayramoğlu, Gökhan; Şentürk, Hakan; Erkasap, Nilüfer; Köken, Tülay; Başer, K. Hüsnü Can (Elsevier GMBH, Urban & Fischer Verlag, 2008)Many plants found in nature have been used to treat various illnesses. One such plant is oregano (Kekik in Turkish). Health beneficial effects of carvacrol obtained from oregano oil have been shown scientifically. We have ... -
Effects of ceranib-2 on cell survival and TNF-alpha in colon cancer cell line
Başpınar, Mustafa Serhat; Özyurt, Rumeysa; Kuş, Gökhan; Kutlay, Özden; Özkurt, Mete; Erkasap, Nilüfer; Kabadere, Selda (Comenius University, 2017)OBJECTIVE: The aim of this study was to investigate the effects of a novel anti-cancer drug, ceranib-2, which targets the acid ceramidase, in human colon cancer cell line. MATERIALS AND METHODS: The cell lines were treated ... -
Erythropoietin Protects the Kidney by Regulating the Effect of TNF-alpha in L-NAME-Induced Hypertensive Rats
Özkurt, Mete; Uzuner, Kubilay; Erkasap, Nilüfer; Kuş, Gökhan; Özyurt, Rumeysa; Uysal, Onur; Kutlay, Özden (Karger, 2018)Background/Aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-alpha plays a major role in inflammation and also depresses the synthesis ... -
Modified method for the determination of capillary electrophoresis nitric oxide-correlated nitrate in tissue homogenates
Tunçel, Muzaffer; Ak, Dilek; Erkasap, Nilüfer (2001)A modified capillary electrophoretic method for the determination of nitric oxide correlated nitrate in several tissue homogenates is described in this study. The method was developed using a running buffer consisting of ...
