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Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors

Tugrak, Mehtap; Gül, Halise İnci; Bandow, Kenjiro; Sakagami, Hiroshi; Gülçin, İlhami; Özkay, Yusuf; Supuran, Claudiu T. (Academic Press Inc Elsevier Science, 2019)

New mono Mannich bases, (2-(4-hydroxy-3-((4-substituephenylpiperazin-1-yl)methyl)benzylidene)-2,3-dihydro-1H-inden-1-one), were prepared to evaluate their cytotoxic/anticancer properties and also their inhibitory effects ...