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Impact of Genetic Factors (CYP2C9, VKORC1 and CYP4F2) on Warfarin Dose Requirement in the Turkish Population
Özer, Mahmut; Demirci, Yeliz; Hızel, Candan; Sarıkaya, Sabit; Karalti, Iskender; Kaspar, Çiğdem; Genç, Ece (Wiley-Blackwell, 2013)Warfarin has a narrow therapeutic index and displays marked person-to-person variation in dose requirement. Functional polymorphisms at candidate genes can therefore offer utility as biomarkers to individualize warfarin ...