Yazar "Genç, Lütfi" için listeleme
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The aggregation behavior of trimetazidine hydrochloride in aqueous solutions at different temperatures
Genç, Lütfi (Elsevier Science BV, 2015)The aggregation behavior of trimetazidine hydrochloride (TMZ HCl) in aqueous solutions has been investigated by electrical conductivity, ultrasonic speed and density measurements in the temperature ranges from 298.15 to ... -
Apoptotic effects of some carbazole derivatives on lung carcinoma and glioma cell lines
Çiftçi, Gülsen Akalın; Temel, Halide Edip; Yıldırım, Şafak Ulusoylar; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Genç, Lütfi (Springer Birkhauser, 2013)In this study, we aimed to study the apoptotic effects of 2-[(9-ethyl-9H-carbazol-3-yl)amino]-2-oxoethyl N,N-disubstituted dithiocarbamates on A549 lung carcinoma and C6 glioma cell lines. Cytotoxicity analyses of DNA ... -
Asiklovir'in biyoadhesiv vajinal tabletleri üzerinde çalışmalar
Oğuzlar, Canan (Anadolu Üniversitesi, 1998)Asiklovir, herpes simpleks veya varisella-zoster virüslerinin sebep olduğu enfeksiyonların tedavisinde kullanılan bir sentetik guanin analogudur. İntravenöz, oral veya lokal olarak uygulanır ve genellikle iyi tolere edilir. ... -
Assessment of Aprotinin Loaded Microemulsion Formulations for Parenteral Drug Delivery: Preparation, Characterization, in vitro Release and Cytotoxicity Studies
Okur, Neslihan Üstündağ; Özdemir, Derya İlem; Kahyaoğlu, Sennur Görgülü; Şenyiğit, Zeynep Ay; Aşıkoğlu, Makbule; Genç, Lütfi; Karasulu, H. Yeşim (Bentham Science Publ LTD, 2016)The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ... -
Audio Book Project in Open and Distance Learning System: Anadolu University Case
Genç, Lütfi; Güler, Erden; Sönmez, Harun (IATED-Int Assoc Technology Education A& Development, 2016)… -
Bioconjugates and Nanocarriers for therapy, imaging, drug design and targeting
Genç, Lütfi (Chemical Publishing Co., 2014)Currently, bioconjugates and nanocarriers can be practically used in drug discovery, therapy, diagnosis, imaging, targeting, stability, etc. Also preparing nano drug carrier systems (NDCSs) is a common application of ... -
Characterization of Solid Lipid Nanoparticles Containing Caffeic Acid and Determination of its Effects on MCF-7 Cells
Dikmen, Gökhan; Güney, Gamze; Genç, Lütfi (Bentham Science Publ LTD, 2015)Many anticancer drugs that are currently used in cancer treatment are natural products or their analogues by structural modification. Caffeic acid (3, 4-dihydroxycinnamic acid; CA) is classified as hydroxycinnamic acid and ... -
The determination of hydralazine hydrochloride by polarography
Tunçel, Muzaffer; Ak, Dilek; Güler, E.; Genç, Lütfi (1993)[No abstract available] -
The determination of ketorolac tromethamine in pharmaceutical preparations by flow injection analysis using UV detection
A flow-injection analysis(FIA) of ketorolac tromethamine(KT) using UV detection is described. The best solvent system was found to be 0.1 mol.l-1 acetate buffer at pH 5.2. A flow rate of lml.min-1 was pumped and active ... -
Determination of micelle formation of ketorolac tromethamine in aqueous media by acoustic measurements
Savaroğlu, Gökhan; Genç, Lütfi (Elsevier Science BV, 2013)Density and speed of sound of ketorolac tromethamine in aqueous solutions have been measured as a function of concentration at atmospheric pressure and in the temperature range from 293.15 to 313.15 K. Apparent molar ... -
The effect of solid lipid nanoparticles on tamoxifen-resistant breast cancer cells
Eskiler, G. Güney; Cecener, G.; Dikmen, G.; Genç, Lütfi; Egeli, U. (Innovare Academics Sciences Pvt. Ltd, 2016)To overcome the acquired Tamoxifen (Tam) resistance in Tam-resistant breast cancer cells without damaging normal cells, we have examined the therapeutic efficacy of Tam-loaded solid lipid nanoparticles (SLNs). Tam-loaded ... -
Effects of Caffeic Acid Incorporated into Solid Lipid Nanoparticles in Cancer Cells
Kutlu, Hatice Mehtap; Güney, Gamze; İşcan, A.; Genç, Lütfi (Crc Press-Taylor & Francis Group, 2011)Nanotechnology has great potential to make an important role in prevention of cancer, detection, diagnosis, imaging and treatment. Solid lipid nanoparticles (SLNs) have been introduced as an alternative drug carrier system. ... -
Effects of caffeic acid incorporated into solid lipid nanoparticles in cancer cells
Kutlu, Hatice Mehtap; Güney, Gamze; İşcan, A.; Genç, Lütfi (2011)Nanotechnology has great potential to make an important role in prevention of cancer, detection, diagnosis, imaging and treatment. Solid lipid nanoparticles (SLNs) have been introduced as an alternative drug carrier system. ... -
Film-coated enteric tablet formulation of ketorolac tromethamine
Genç, Lütfi; Güler, Erden; Hegazy, Nahed (Informa Healthcare, 1997)A great majority of polymers used for pharmaceutical film-coating purposes have been derivatives of cellulose or methacrylate copolymers (Eudragit series) in most recent studies. The type and frequency of the ester ... -
Formulation and stability of parenteral hydralazine hydrochloride
Genç, Lütfi; Güler, Erden (1991)[No abstract available] -
Hidralizin hidroklorürün formülasyonu ve stabilitesi
Genç, Lütfi (Anadolu Üniversitesi, 1989)Bu çalışmada, hidralazin hidroklorür'ün parenteral formülas- yonları ve bunların stabilitesi üzerinde çalışılmıştır. Koruyucu olarak metil paraben, propil paraben, benzalkonyum klorür ve benzil alkol içeren ampüllerde ... -
The Impact of Caffeic Acid Loaded Solid Lipid Nanoparticles on Cancer Treatment
Kutlu, Hatice Mehtap; Genç, Lütfi; Güney, Gamze (Bentham Science Publ LTD, 2013)In an attempt to develop caffeic acid for drug delivery, caffeic acid-loaded solid lipid nanoparticles (CA-SLNs) were constructed, and were characterized to determine their properties followed by their evaluation for in ... -
In vitro evaluation of sustained released matrix tablet formulations of clarithromycin
Genç, Lütfi; Kıran, A. M. (Osterreichische Apotheker-Verlagsgesellschaft m.b.H., 2005)Sustained release matrix tablets of clarithromycin were prepared using different polymers as Hydroxypropyl methylcellulose (HPMC), Carbopol 934 and Eudragit RL/PO by direct compression technique. For the quality control ... -
Inclusion complexes of fluconazole with beta-cyclodextrin: physicochemical characterization and in vitro evaluation of its formulation
Yurtdaş Kırımlıoğlu, Gülsel; Demirel, Müzeyyen; Genç, Lütfi (Springer, 2011)Fluconazole (FZ) is a triazole antifungal drug administered orally or intravenously. It is employed for the treatment of mycotic infections. However, the efficacy of FZ is limited with its poor aqueous solubility and low ...
