Yazar "Gulcin, Ilhami" için listeleme
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The Influence of Some Nonsteroidal Anti-inflammatory Drugs on Metabolic Enzymes of Aldose Reductase, Sorbitol Dehydrogenase, and alpha-Glycosidase: a Perspective for Metabolic Disorders
Demir, Yeliz; Duran, Hatice Esra; Durmaz, Lokman; Taslimi, Parham; Beydemir, Sukru; Gulcin, Ilhami (Springer, 2020)Pain, as a sensible alarm signal of living organisms to avoid tissue damage, is a common and debilitating consequence of a lot of disorders and diseases. the management of chronic pain is particularly challenging. For pain ... -
Inhibition effects of some pesticides and heavy metals on carbonic anhydrase enzyme activity purified from horse mackerel (Trachurus trachurus) gill tissues
Caglayan, Cuneyt; Taslimi, Parham; Turk, Cebrahil; Gulcin, Ilhami; Kandemir, Fatih Mehmet; Demir, Yeliz; Beydemir, Sukru (Springer Heidelberg, 2020)The gill tissue is the main site of metabolic enzymes or compensation, with the kidney tissue playing a supporting role. At the gill tissue, carbonic anhydrase enzymes (CAs) catalyze the hydration of CO2 to HCO3- and H+ ... -
Screening of non-alkaloid acetylcholinesterase and carbonic anhydrase isoenzymes inhibitors of Leiotulus dasyanthus (K. Koch) Pimenov & Ostr. (Apiaceae)
Karakaya, Songul; Bingol, Zeynebe; Koca, Mehmet; Demirci, Betul; Gulcin, Ilhami; Baser, K. Husnu Can (Taylor & Francis Inc, 2020)The oxidant, cholinesterase, and carbonic anhydrase inhibitions of essential oils and their major compounds of Leiotulus dasyanthus and molecular docking studies of alpha-pinene and (TM)-3-carene were evaluated in this ... -
Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3-diaryltriazene-substituted sulfathiazole derivatives
Isik, Mesut; Akocak, Suleyman; Lolak, Nabih; Taslimi, Parham; Turkes, Cuneyt; Gulcin, Ilhami; Beydemir, Sukru (Wiley-V C H Verlag Gmbh, 9999)In the present study, a series of eleven novel 1,3-diaryltriazene-substituted sulfathiazole moieties (ST1-11) was synthesized by the reaction of diazonium salt of sulfathiazole with substituted aromatic amines and their ... -
Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones
Bilginer, Sinan; Gul, Halise Inci; Erdal, Feyza Sena; Sakagami, Hiroshi; Levent, Serkan; Gulcin, Ilhami; Supuran, Claudiu T. (Taylor & Francis Ltd, 2019)In this study, new chalcone compounds having the chemical structure of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones (1?8) were synthesised and were characterised by H-1-NMR, C-13?-NMR, and HRMS spectra. Cytotoxic and carbonic ... -
Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes
Yamali, Cem; Gul, Halise Inci; Kazaz, Cavit; Levent, Serkan; Gulcin, Ilhami (Academic Press Inc Elsevier Science, 2020)A novel series of 4-(3-(difluorophenyl)-5-(dimethoxyphenyl)-4,5-dihydropyrazol-1-yl)benzenesulfonamides 1-8 were designed since sulfonamide and pyrazoline pharmacophores draw great attention in novel drug design due to ...
