Browsing by Author "Horta, Pedro"

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Quinolone-Hydroxyquinoline Tautomerism in Quinolone 3-Esters. Preserving the 4-Oxoquinoline Structure To Retain Antimalarial Activity

Horta, Pedro; Kuş, Nihal; Henriques, Marta Sofia C.; Paixao, Jose A.; Coelho, Lis; Nogueira, Fatima; Santos Cristiano, Maria Lurdes (American Chemical Society, 2015)

Recent publications report in vitro activity of quinolone 3-esters against the bc(1) protein complex of Plasmodium falciparum and the parasite. Docking studies performed in silica at the yeast Q(o) Site established a key ...