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Antioxidant and Antiradical Properties of Selected Flavonoids and Phenolic Compounds
Huyut, Zubeyir; Beydemir, Şükrü; Gülçin, İlhami (Hindawi LTD, 2017)Phenolic compounds and flavonoids are known by their antioxidant properties and one of the most important sources for humans is the diet. Due to the harmful effects of synthetic antioxidants such as BHA and BHT, natural ... -
The effects of some cephalosporins on acetylcholinesterase and glutathione S-transferase: an in vivo and in vitro study
Türkan, Fikret; Huyut, Zubeyir; Demir, Yeliz; Ertaş, Fatma; Beydemir, Şükrü (Taylor & Francis LTD, 2019)Background: Glutathione S-transferase (GST) and acetylcholinesterase (AChE) are important enzymes in the metabolism. GSTs are primarily available in phase II metabolism. AChE is vital for neurodegenerative disorders. ... -
Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes
Huyut, Zubeyir; Beydemir, Şükrü; Gülçin, İlhami (Wiley, 2017)Carbonic anhydrases (CAs, E.C.4.2.1.1) play a critical role in many important physiological events and treatment of some diseases. Flavonoids or phenolic compounds have been discovered as novel CAs inhibitors instead of ... -
Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors
Gülçin, İlhami; Abbasova, Malahat; Taslimi, Parham; Huyut, Zubeyir; Safarova, Leyla; Sujayev, Afsun; Supuran, Claudiu T. (Taylor & Francis LTD, 2017)Compounds containing nitrogen and sulfur atoms can be widely used in various fields such as industry, medicine, biotechnology and chemical technology. Therefore, the reactions of aminomethylation and alkoxymethylation of ...