Yazar "Koparal, Ayşe Tansu" için listeleme
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Adhesion profile and differentiation capacity of human adipose tissue derived mesenchymal stem cells grown on metal ion (Zn, Ag and Cu) doped hydroxyapatite nano-coated surfaces
Bostancıoğlu, R. Beklem; Gürbüz, Mevlüt; Akyürekli, Ayşe Gül; Doğan, Aydın; Koparal, Ali Savaş; Koparal, Ayşe Tansu (Elsevier Science BV, 2017)Accelerated Mesenchymal Stem Cells (MSCs) condensation and robust MSC-matrix and MSC-MSC interactions on nano-surfaces may provide critical factors contributing to such events, likely through the orchestrated signal cascades ... -
Analyses of the modulatory effects of antibacterial silver doped calcium phosphate-based ceramic nano-powder on proliferation, survival, and angiogenic capacity of different mammalian cells in vitro
Bostancıoğlu, R. Beklem; Peksen, Ceren; Genç, Hatice; Gürbüz, Mevlüt; Karel, Filiz Bayrakci; Koparal, Ali Savaş; Koparal, Ayşe Tansu (IOP Publishing LTD, 2015)In this study, the antibacterial, cytotoxic, and angiogenic activities of silver doped calcium phosphate-based inorganic powder (ABT or PAG) were systematically investigated. ABT powders containing varying silver content ... -
Angiogenesis Inhibition by A Lichen Compound Olivetoric Acid
Koparal, Ayşe Tansu; Ulus, Gönül; Zeytinoğlu, Melih; Tay, Turgay; Türk, Ayşen Özdemir (Wiley-Blackwell, 2010)Lichens have been used in folk medicine for centuries and are symbiotic organisms of fungi and algae that produce unique secondary metabolites. Olivetoric acid is one of these secondary metabolites. In the present studs ... -
The anti-angiogenic activity of Artemisia herba-alba's essential oil and its relation with the harvest period
Jaouadi, I.; Koparal, Ayşe Tansu; Bostancıoğlu, Rakibe Beklem; Yakoubi, M. T.; El, Gazzah, M. (Southern Cross Publishing and Printing Pty Ltd, 2014)Artemisia herba-alba is widely used in traditional medicine to treat diabetes, bronchitis, diarrhoea, hypertension and neuralgias. The aim of this study is to investigate the essential oil extracted from the aerial part ... -
Anti-angiogenic and antiproliferative properties of the lichen substances (-)-usnic acid and vulpinic acid
Koparal, Ayşe Tansu (Walter De Gruyter GMBH, 2015)The anti-proliferative activities of the lichen substances (-)-usnic acid and vulpinic acid on the viability of HepG2 hepatocarcinoma cells, NS20Y neuroblastoma cells and HUVEC endothelial cells were studied by the MTT ... -
The anti-angiogenic potential of (+/-) gossypol in comparison to suramin
Ulus, Gönül; Koparal, Ayşe Tansu; Baysal, Kemal; Yetik Anacak, Günay; Yavaşoğlu, N. Ülkü Karabay (Springer, 2018)Cotton, a staple fiber that grows around the seeds of the cotton plants (Gossypium), is produced throughout the world, and its by products, such as cotton fibers, cotton-seed oil, and cottonseed proteins, have a variety ... -
Anti-lung Cancer and Anti-angiogenic Activities of New Designed Boronated Phenylalanine Metal Complexes
Varol, Mehmet; Koparal, Ayşe Tansu; Benkli, Kadriye; Bostancıoğlu, Rakibe Beklem (Bentham Science Publ LTD, 2018)Background: Drug design and discovery studies still remain of great importance in the search for more convenient chemotherapeutic to avoid the drug resistance, systemic toxicity or the long-term side effects. Objective: A ... -
Assesment of Combined Activity of Erlotinib With Classical Chemotherapeutics on Jar Cell Line
Özalp, S. Sinan; Telli, E.; Genç, Hatice; Altuğ, B.; Koparal, Ayşe Tansu (Lippincott Williams & Wilkins, 2015)… -
Assessment of anti-angiogenic and anti-tumoral potentials of Origanum onites L. essential oil
Bostancıoğlu, R. Beklem; Kürkçüoğlu, Mine; Başer, K. Hüsnü Can; Koparal, Ayşe Tansu (Pergamon-Elsevier Science LTD, 2012)Medicinal plants and culinary herbs with anti-angiogenic and little toxicity properties have gained importance. Non-toxic anti-angiogenic phytochemicals are useful in combating cancer by preventing the formation of new ... -
Assessment of in vitro cytotoxic and genotoxic activities of some trimethoprim conjugates
Bayulken, Devrim Güzel; Bostancıoğlu, Rakibe Beklem; Koparal, Ayşe Tansu; Tüylü, Berrin; Dağ, Aydan; Benkli, Kadriye (Springer, 2018)Trimethoprim, a commonly used antibacterial agent, is widely applied in the treatment of variety of infections in human. A few studies have demonstrated an extensive exposure of man to antibiotics, but there is still a ... -
Biocompatibility of designed MicNo-ZnO particles: Cytotoxicity, genotoxicity and phototoxicity in human skin keratinocyte cells
Genç, Hatice; Barutca, Banu; Koparal, Ayşe Tansu; Özogut, Uğurcan; Şahin, Yücel; Suvacı, Ender (Pergamon-Elsevier Science LTD, 2018)Recently, designed platelet shaped micron particles that are composed of nano primary particles, called MicNo (= Micron + naNo) particles, have been developed to exploit the benefits of nano size, while removing the adverse ... -
Cryptic fragment ?4 LG4-5 derived from laminin ?4 chain inhibits de novo adipogenesis by modulating the effect of fibroblast growth factor-2
Yamanaka, Hiroaki; Goto, Chie; Tajima, Rie; Koparal, Ayşe Tansu; Kobori, Masato; Ohki, Yuji; Kitagawa, Y. (2008)Cleavage of the extracellular matrix (ECM) by proteolysis unmasks cryptic sites and generates novel fragments with biological activities functionally distinct from those of the intact ECM molecule. The laminin G-like (LG)4-5 ... -
Cryptic fragment alpha 4 LG4-5 derived from laminin alpha 4 chain inhibits de novo adipogenesis by modulating the effect of fibroblast growth factor-2
Yamashita, Hironobu; Goto, Chie; Tajima, Rie; Koparal, Ayşe Tansu; Kobori, Masato; Ohki, Yuji; Kitagawa, Yasuo (Blackwell Publishing, 2008)Cleavage of the extracellular matrix (ECM) by proteolysis unmasks cryptic sites and generates novel fragments with biological activities functionally distinct from those of the intact ECM molecule. The laminin G-like (LG)4-5 ... -
Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp siculum
Rosselli, Sergio; Bruno, Maurizio; Raimondo, Francesco Maria; Spadaro, Vivienne; Varol, Mehmet; Koparal, Ayşe Tansu; Maggio, Antonella (MDPI, 2012)A phytochemical analysis of the dichloromethane extract from the flowers of a subspecies of Tanacetum vulgare growing in Sicily was carried out. Five known sesquiterpene lactones with the eudesmane skeleton have been ... -
Cytotoxic effects of various lactic acid bacteria on Caco-2 cells
Er, Sevda; Koparal, Ayşe Tansu; Kıvanç, Merih (Tubitak Scientific & Technical Research Council Turkey, 2015)Probiotics are live microbial food supplements that can be considered a functional food. They benefit the health of a host animal by maintaining their intestinal microbial balance. Most probiotic microorganisms are lactic ...
