Yazar "Korkmaz, Orhan Tansel" için listeleme
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Determination of carbamazepine and its main metabolite carbamazepine-10, 11-epoxide in rat brain microdialysate and blood using ESI-LC-MS (ion trap)
Şener, E.; Korkmaz, Orhan Tansel; Yeniceli, Duygu; Ak, Dilek; Tunçel, Muzaffer; Tuncel, N. (Springer Heidelberg, 2007)A new analytical method has been developed and validated for determination of the anti-epileptic drug carbamazepine (CBZ) and its main metabolite carbamazepine- 10, 11 -epoxide (CBZ-E) using ESl-LC-MS (ion trap). The ... -
Determination of Ochratoxin-A in the brain microdialysates and plasma of awake, freely moving rats using ultra high performance liquid chromatography fluorescence detection method
Kaya, Erbil Melek Özlem; Korkmaz, Orhan Tansel; Uğur, Duygu Yeniceli; Şener, Erol; Tuncel, A. Neşe; Tunçel, Muzaffer (Elsevier, 2019)In this study, a simple, efficient and rapid Ultra High Performance Liquid Chromatography method with fluorescence detection (UHPLC-FLD) has been developed and validated for the determination of Ochratoxin-A (OTA) in rat ... -
The Effects of Vasoactive Intestinal Peptide on Dura Mater Nitric Oxide Levels and Vessel-Contraction Responses in Sympathectomized Rats
Töre, Fatma; Korkmaz, Orhan Tansel; Ak, Dilek; Tuncel, Neşe (Humana Press Inc, 2010)Nitric oxide (NO) and neurogenic inflammation in dura mater due to nociceptor activation has been implicated for pathophysiology of primary headache disorders. Development of migraine has also been observed in patients ... -
Modulation of Corpus Striatal Neurochemistry by Astrocytes and Vasoactive Intestinal Peptide (VIP) in Parkinsonian Rats
Yelkenli, İbrahim Halil; Ulupınar, Emel; Korkmaz, Orhan Tansel; Şener, Erol; Kuş, Gökhan; Filiz, Zeynep; Tuncel, Neşe (Humana Press Inc, 2016)The neurotoxin 6-hydroxydopamine (6-OHDA) is widely used in animal models of Parkinson's disease. In various neurodegenerative diseases, astrocytes play direct, active, and critical roles inmediating neuronal survival and ... -
A simple and sensitive LC-ESI-MS (ion trap) method for the determination of bupropion and its major metabolite, hydroxybupropion in rat plasma and brain microdialysates
Yeniceli, Duygu; Şener, Erol; Korkmaz, Orhan Tansel; Ak, Dilek; Tuncel, Neşe (Elsevier Science BV, 2011)A specific and highly sensitive liquid chromatography-electrospray mass spectrometry (LC-ESI-MS) method for the direct determination of bupropion (BUP) and its main metabolite hydroxybupropion (HBUP) in rat plasma and brain ... -
Vasoactive Intestinal Peptide (Vip) Treatment of Parkinsonian Rats Increases in Thalamic Gamma Amino Butyric Acid (Gaba) Levels, and Changes Nerve Growth Factor (Ngf) Release of Brain Mast Cells
Tuncel, Neşe; Korkmaz, Orhan Tansel; Tunçel, Muzaffer; Öncü-Kaya, Elif Mine; Şahintürk, Varol; Çelik, Mustafa (Churchill Livingstone, 2009)… -
Vasoactive Intestinal Peptide (VIP) Treatment of Parkinsonian Rats Increases Thalamic Gamma-Aminobutyric Acid (GABA) Levels and Alters the Release of Nerve Growth Factor (NGF) by Mast Cells
Korkmaz, Orhan Tansel; Tuncel, Neşe; Tunçel, Muzaffer; Öncü-Kaya, Elif Mine; Şahintürk, Varol; Çelik, Mustafa (Humana Press Inc, 2010)The ventral anterior nucleus of the thalamus (VATh) gathers motor information from the internal segment of the globus pallidus (GPi) and substantia nigra pars reticulata (SNpr) of the basal ganglia and projects directly ...
