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A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death
Mbaveng, Armelle T.; Ndontsa, Blanche L.; Kuete, Victor; Nguekeu, Yves M. M.; Çelik, İlhami; Mbouangouere, Roukayatou; Efferth, Thomas (Elsevier GMBH, Urban & Fischer Verlag, 2018)Introduction: Multidrug resistance of cancer cells constitutes a serious problem in chemotherapy and a challenging issue in the discovery of new cytotoxic drugs. Many saponins are known to display anti-cancer effects. In ...