Yazar "Okur, Mehmet Evren" için listeleme
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Capparis ovata var. palaestina bitkisinin farelerde hipoglisemik etkilerinin ve mekanizmasının araştırılması
Okur, Mehmet Evren (Anadolu Üniversitesi, 2016)Diabetes mellitus (DM), insu?linin salgılanması ve/veya insu?linin hedef dokulardaki etkisi üzerinde gelişen bozukluklardan kaynaklanan, özellikle hiperglisemi ile karakterize, karbonhidrat, lipid ve protein metabolizması ... -
Characterization of Opuntia ficus-indica (L.) Mill. fruit volatiles and antibacterial evaluation
Karadağ, A. E.; Demirci, Betül; Polat, D. Ç.; Okur, Mehmet Evren (Badebio Biotechnololgy Ltd, 2018)Opuntia ficus-indica (L.) Mill. fruits known as prickly pear cactus are used in folk medicine as well as food. In the present study it was aimed to extract the volatile constituents of O. ficus-indica fruits by n-hexane. ... -
Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity; physicochemical properties, in vitro release and oral acute toxicity
Siafaka, Panoraia; Okur, Mehmet Evren; Ayla, Şule; Er, Sevda; Çaglar, Emre Şefik; Okur, Neslihan Üstündağ (University Sao Paulo, Conjunto Quimicas, 2019)Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica ... -
Diabetes mellitus: A review on pathophysiology, current status of oral medications and future perspectives
Okur, Mehmet Evren; Karantas, I. D.; Siafaka, P. I. (University of Istanbul, 2017)Diabetes mellitus (DM), belongs to the class of metabolic diseases which the main symptom associated with this disease is the high sugar levels in blood for a long period. It can be categorized to the world’s major diseases ... -
Effects of Prunus spinosa L. Fruits on experimental wound healing [Prunus spinosa L. Meyvelerinin deneysel yara iyileşmesi üzerine etkileri]
Ayla, Şule; Günal, Yalçın Mehmet; Sayin, Şakul, A. A.; Biçeroğlu, Ö.; Özdemir, E. M.; Okur, Mehmet Evren (Logos Medical Publishing, 2017)We investigated the wound healing efficacy of the methanol extracts of Prunus spinosa L. fruits using an excisional cutaneous wound model in mice. We used 32 C57/Black mice equally divided into four groups. Group 1 Control, ... -
Evaluation of the Antidiabetic Property of Capparis Ovata Desf. Var. Palaestina Zoh. Extracts Using In vivo and In vitro Approaches
Okur, Mehmet Evren; Polat, Derya C.; Özbek, Hanefi; Yılmaz, Sezen; Yoltas, Ayşegül; Arslan, Rana (Bentham Science Publ LTD, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Hypoglycemic activity of Capparis ovata desf. var. palaestina zoh. methanol extract
Okur, Mehmet Evren; Özbek, Hanefi; Polat, Derya Çiçek; Yılmaz, Sezen; Arslan, Rana (University Sao Paulo, Conjunto Quimicas, 2018)Caper (Capparis ovata Desf. and Capparis spinosa L.) is naturally widespread in Turkey. Traditionally, buds, fruits, seeds and roots of this plant arc used as tonic, diuretic, anti-rheumatic, expectorant, antidiabetic, and ... -
In vitro antibacterial, antioxidant, anti-inflammatory and analgesic evaluation of Rosmarinus officinalis L. flower extract fractions
Karadağ, A. E.; Demirci, Betül; Çaşkurlu, A.; Demirci, Fatih; Okur, Mehmet Evren; Orak, D.; Başer, K. Hüsnü Can (Elsevier B.V., 2019)Rosmarinus officinalis L. (rosemary) is a common culinary spice and herbal drug, which is used for centuries all over the world. In this present study, apolar to polar fractions of R. officinalis flowers were evaluated for ... -
In vitro cytotoxicity evaluation of Marrubium vulgare L. methanol extract
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Aye Esra; Yılmaz, Rabia; Demirci, Fatih (Marmara University, 2019)Marrubiuni vulgare L. (Lamiaceae) is a herbal drug used for centuries for many diseases. In this present study the plant material was acquired from commercial sources in pharma grade (PhEur 8.0) quality. The methanol extract ... -
Investigation of antioxidant and cytotoxic activities of Opuntia ficus-indica (L.) Mill. fruit extract
Okur, Mehmet Evren; Karakas, Nihal; Karadag, Ayse Esra; Uludag, Damla; Polat, Derya Cicek (Istanbul Univ, Fac Pharmacy, 2019)Opuntia ficus-indica fruits are claimed to possess several health-beneficial properties. This study was carried out to determine the phytochemicals as well as to compare antioxidant activity and cell viability of the ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
Okur, Neslihan Üstündağ; Filippousi, Maria; Okur, Mehmet Evren; Ayla, Şule; Çaglar, Emre Şefik; Yoltas, Ayşegül; Siafaka, Panoraia, I (Elsevier Science BV, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ... -
Novel insight into wound healing properties of methanol extract of Capparis ovata Desf. var. palaestina Zohary fruits
Okur, Mehmet Evren; Ayla, Şule; Polat, Derya Çiçek; Günal, Mehmet Y.; Yoltas, Ayşegül; Biçeroğlu, Özge (Wiley, 2018)ObjectivesThe objective of this study was to investigate the wound healing activity of Capparis ovata var. palaestina fruit extract in mice. For this aim, wound healing, invitro antimicrobial and antioxidant activities, ...