Yazar "Otsuka, Masami" için listeleme
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Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
Sever, Belgin; Altıntop, Mehlika Dilek; Radwan, M. O.; Özdemir, Ahmet; Otsuka, Masami; Fujita, M.; Çiftçi, H. I. (Elsevier Masson SAS, 2019)Epidermal growth factor receptor (EGFR, also known as HER1) and HER2, prominent members of receptor tyrosine kinase (RTK) superfamily, have been reported as diagnostic or prognostic markers in tumor progression. Based on ... -
Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
Karabacak, Muhammed; Altıntop, Mehlika Dilek; Çiftçi, Halil İbrahim; Koga, Ryoko; Otsuka, Masami; Fujita, Mikako; Özdemir, Ahmet (MDPI AG, 2015)New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines. 1-[((5-(4-Methylphenyl)-1,3,4-oxadiazol-2-yl)th ...
