Yazar "Sivas, Hülya" için listeleme
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Activated N-ras oncogene inhibits the expression of PDGF-BB receptor in myoblast cells
Sivas, Hülya; Griffiths, S. L. (Elsevier Sci Ireland LTD, 2001)… -
Activated N-ras oncogene inhibits the expression of PDGF-beta receptor in myoblast cells
Sivas, Hülya; Griffiths, S. L.; Gibson, I (Inst Exp Pathol Oncol Radiobiol, 2002)By RT-PCR technique mRNA levels of platelet-derived growth factor type-beta receptor (PDGF-beta-R) and MyoD1 in a myoblast cell line carrying human N-ras oncogene have been investigated. After dexamethasone treatment an ... -
Androctonus Crassicauda Ham Venomundan BC3H1 Hücrelerine Sitotoksik Etkili Ac8, Ac9 ve Ac10 Peptidlerinin Saflaştırılması
Çalışkan, Figen; Sivas, Hülya; Şahin, Yalçın (Anadolu Üniversitesi, 2009)Akrepler çok sayıda biyoaktif bileşen içeren venomlarmı avlanma ya da savunma amaçlı kullanan arahnid grubundan canlılardır. Türkiye’de ölümcül zehirlenmelere neden olan iki tür Leiurus quen-questriatus ve Androctonus ... -
The antimutagenic and antimitotic properties of the extract of the lichen Cetraria aculeata
Sivas, Hülya; Seller, Zerrin; Tüylü, Berrin; Türk, A; Barutca, B (Academic Press Inc Elsevier Science, 2004)… -
Antiproliferative and Apoptotic Effects of the Essential Oil of Origanum Onites and Carvacrol on Hep-G2 Cells
Sivas, Hülya; Tomsuk, Özlem (Anadolu Üniversitesi, 2011)The essential oil Origanum onites L. and its phenolic constituent carvacrol were examined for their cytotoxic and apoptotic effects in a human hepatocellular carcinoma cells Hep-G2. WST-1 and neutral red uptake assays were ... -
Biological activities of Cu(II) and Hg(II) complexes of a heptadentate Schiff base ligand
Ergene, Emel; Sivas, Hülya; Benkli, Kadriye (Tubitak Scientific & Technical Research Council Turkey, 2010)Two metal complexes were synthesized as [Hg(L)](ClO4)(2) and [Cu(L)](ClO4), by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of Hg(II) and ... -
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
Çalışkan, Figen; Ergene, Emel; Sögüt, İbrahim; Hatipoğlu, İbrahim; Basalp, Aynur; Sivas, Hülya; Kanbak, Güngör (Pergamon-Elsevier Science LTD, 2013)Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ... -
Characterisation of dorylaion (Turkey) pottery sherds from Hittite period
Kara, Alpagut; Darga, M; Ay, Nuran; Ayaş, E; Sivas, Taciser; Sivas, Hülya (Trans Tech Publications LTD, 2004)In this study, representative samples were taken from eleven pottery sherds of Hittite period recovered during the archaeological excavations of different years in the ancient city Dorylaion, which is nowadays called as ... -
Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae)
Ünlü, Mehmet; Ergene, Emel; Ünlü, Gülhan Vardar; Sivas, Hülya; Vural, Nilüfer (Pergamon-Elsevier Science LTD, 2010)The essential oil from the bark of Cinnamomum zeylanicum Blume was analyzed by GC-MS and bioassays were carried out. Nine constituents representing 99.24% of the oil were identified by GC-MS. The major compounds in the oil ... -
Cytosolic $Ca^{2+}$ levels in CO25 myoblast cells bearing a human N-ras oncogene after stimulation by thapsigargin and growth factors
Zeytinoğlu, Hülya; Gıbson, Ian (1999)CO25 miyoblast hücrelerinin, thapsigargin (ThG), bombesin ve epidermal büyüme faktörü (EGF) ile stimülasyonları sonucunda hücre içi kalsiyum [$Ca^{2+}$ ]i seviyeleri araştırılmıştır. ThG, çoğunlukla hücre içi kalsiyum ... -
Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells
Kuete, Victor; Omosa, Leonidah K.; Tala, Viviane R. Sipowo; Midiwo, Jacob O.; Mbaveng, Armelle T.; Swaleh, Sauda; Sivas, Hülya (Bmc, 2016)Background: Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases. Methods: This study was designed to investigate the cytotoxicity of ... -
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
Kuete, Victor; Ngnintedo, Dominique; Fotso, Ghislain W.; Karaosmanoğlu, Oğuzhan; Ngadjui, Bonaventure T.; Keumedjio, Felix; Sivas, Hülya (Bmc, 2018)Background: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective ... -
Cytotoxicity of the methanol extracts of Elephantopus mollis, Kalanchoe crenata and 4 other Cameroonian medicinal plants towards human carcinoma cells
Kuete, Victor; Fokou, Fabrice W.; Karaosmanoğlu, Oğuzhan; Beng, Veronique P.; Sivas, Hülya (Bmc, 2017)Background: Cancer still constitutes one of the major health concerns globally, causing serious threats on patients, their families, and the healthcare system. Methods: In this study, the cytotoxicity of the methanol extract ... -
Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro
Sivas, Hülya; Seller, Zerrin; Tüylü, Berrin; Türk, A. O.; Barutca, B. (Wiley, 2008)Naturally occurring compounds can have protective effects towards mutagens and carcinogens as shown by numerous studies. In the present study, the genotoxic/antigenotoxic activities of the extract from lichen Cetraria ... -
Effects of carvacrol on gene expression involved in MAPK - Pathway in DLD-1 and CCL-241 cells
Sivas, Hülya; Ergene, Emel (Elsevier Science BV, 2016)… -
Effects of carvacrol on sister chromatid exchanges in human lymphocyte cultures
İpek, E; Tüylü, Berrin; Sivas, Hülya (Springer, 2003)Carvacrol is a predominant aromatic compound in oil of oregano. It has naturally remarkable antibacterial, antiviral, antifungal and antiparasital effects. In this study, genotoxic and antigenotoxic activities of carvacrol ... -
Effects of carvacrol on the expression of genes involved in MAP-kinase pathway in Hep-G2 cells
Sivas, Hülya; Ergene, Emel; Tomsuk, Özlem (Current Biology LTD, 2013)… -
Effects of fibronectin and type IV collagen on osteosarcoma cell apoptosis
Seller, Zerrin; Hatipoğlu, İbrahim; Sivas, Hülya; Ergene, Emel; Çiftçi, Gülsen Akalın (Natl Inst Science Communication-Niscair, 2013)The aims of this study are the investigation of the effects of fibronectin and type IV collagen extracellular matrix proteins and the role of caspase-3 and -9 on cis-platin induced U2-OS apoptosis were studied. First the ... -
The effects of n-ras oncogene expression on PDGF-BB stimulated responses in cultured mouse myoblasts
Sivas, Hülya; Griffiths, S. L.; Dawson, A. P.; Gibson, I. (1995)The role of the ras oncogene in the signalling pathway triggered by platelet-derived growth factor BB (PDGF-BB) has been investigated in a cell line which normally differentiates into myotubes. Following the activation of ...
