Yazar "Türkeş, Cüneyt" için listeleme
-
Anti-diabetic Properties of Calcium Channel Blockers: Inhibition Effects on Aldose Reductase Enzyme Activity
Türkeş, Cüneyt; Demir, Yeliz; Beydemir, Şükrü (Springer, 2019)Aldose reductase (AR) belongs to NADPH-dependent oxidoreductases and converts glucose to sorbitol in the polyol pathway. AR inhibition is essential to prevent diabetic complications. Here, AR was purified from sheep kidney ... -
Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies
Beydemir, Şükrü; Türkeş, Cüneyt; Yalçın, Ahmet (Taylor & Francis LTD, 2019)Medications show their biological effects by interaction with enzymes, which have been known to play an essential role in the pathogenesis of many diseases. Inhibition or induction of drug metabolizing enzymes has an ... -
Inhibition of Human Serum Paraoxonase-I with Antimycotic Drugs: In Vitro and In Silico Studies
Türkeş, Cüneyt; Beydemir, Şükrü (Humana Press Inc., 2019)Drugs show their pharmacological effects by inhibiting or activating enzymes. Therefore, enzyme inhibitors have an essential place in the drug design for numerous different sorts of diseases, i.e., cardiovascular, cancer, ... -
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors
Türkeş, Cüneyt; Arslan, Mustafa; Demir, Yeliz; Cocaj, Liridon; Nixha, Arleta Rıfati; Beydemir, Şükrü (Academic Press Inc Elsevier Science, 2019)The synthesis, characterization and biological evaluation of a series of novel N-substituted phthalazine sulfonamide (5a-1) are disclosed. Phthalazines which are nitrogen-containing heterocyclic compounds are biologically ...
