Yazar "Uzun, Lokman" için listeleme
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Amino acid conjugated self assembling molecules for enhancing surface wettability of fiber laser treated titanium surfaces
Akkan, Çağrı K.; Hür, Deniz; Uzun, Lokman; Garipcan, Bora (Elsevier Science BV, 2016)Surface wetting properties of implants are one of the most critical parameter, which determine the interaction of proteins and cells with the implant surface. In this regards, acid etching and sand blasting are the mostly ... -
Amino Acid Conjugated Self Assembly Molecules Modified Si Wafers
Aktaş, Bengü; Uzun, Lokman; Hür, Deniz; Garipcan, Bora (IEEE, 2014)In this study, Si wafer surface was modified with newly synthesized self-assembled monolayers to mimic a biocompatible micro-environment for the cells and to observe their behavior. Begin with; Si wafer is chosen as its ... -
Amino acid conjugated self assembly molecules modified Si wafers [Amino asit konjuge kendili?inden düzenlenen moleküller ile si pulcuklari{dotless}n modifikasyonu]
Aktaş, Bengü; Uzun, Lokman; Hür, Deniz; Garipcan, Bora (Institute of Electrical and Electronics Engineers Inc., 2003)In this study, Si wafer surface was modified with newly synthesized self-assembled monolayers to mimic a biocompatible micro-environment for the cells and to observe their behavior. Begin with; Si wafer is chosen as its ... -
Aspartic acid incorporated monolithic columns for affinity glycoprotein purification
Armutcu, Canan; Bereli, Nilay; Bayram, Engin; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2014)Novel aspartic acid incorporated monolithic columns were prepared to efficiently affinity purify immunoglobulin G (IgG) from human plasma. The monolithic columns were synthesised in a stainless steel HPLC column (20 cm x ... -
Bitargeting and ambushing nanotheranostics
Say, Rıdvan; Uzun, Lokman; Yazar, Suzan; Denizli, Adil; Hür, Deniz; Yılmaz, Filiz; Ersöz, Arzu (Informa Healthcare, 2014)The main problem in cancer chemotherapy is the cytotoxic side effects of therapeutics on healthy tissues and cells. The targeted drug delivery and nanotechnology are intensively investigated area to find new ways to solve, ... -
Chiral recognition of proteins having L-histidine residues on the surface with lanthanide ion complex incorporated-molecularly imprinted fluorescent nanoparticles
Uzun, Lokman; Uzek, Recep; Şenel, Serap; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2013)In this study, lanthanide ion complex incorporated molecularly imprinted fluorescent nanoparticles were synthesized. A combination of three novel approaches was applied for the purpose. First, lanthanide ions [Terbium(III)] ... -
F-ab fragments imprinted SPR biosensor for real-time human immunoglobulin G detection
Ertürk, Gizem; Uzun, Lokman; Tümer, M. Aşkın; Say, Rıdvan; Denizli, Adil (Elsevier Advanced Technology, 2011)F-ab fragments imprinted surface plasmon resonance (SPR) chip was prepared for the real-time detection of human immunoglobulin G (IgG). In order to attach polymerization precursor on SPR chip, the SPR chip surface was ... -
Hepatitis B surface antibody purification with hepatitis B surface antibody imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-tyrosine methyl ester) particles
Uzun, Lokman; Say, Ridvon; Ünal, Serhat; Denizli, Adil (Elsevier Science BV, 2009)Hepatitis B surface antibody imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-tyrosine methyl ester) particles were prepared for the purification of hepatitis B surface antibody from human plasma. N-methacryloyl ... -
Hydrophobic cryogels for DNA adsorption: Effect of embedding of monosize microbeads into cryogel network on their adsorptive performances
Corman, Mehmet Emin; Bereli, Nilay; Özkara, Serpil; Uzun, Lokman; Denizli, Adil (Wiley-Blackwell, 2013)As alternative hydrophobic adsorbent for DNA adsorption, supermacroporous cryogel disks were synthesized via free radical polymerization. In this study, we have prepared two kinds of cryogel disks: (i) poly(2-hydroxyethyl ... -
Hydrophobic microbeads as an alternative pseudo-affinity adsorbent for recombinant human interferon-alpha via hydrophobic interactions
Saylan, Yeseren; Sarı, Mufrettin Murat; Özkara, Serpil; Uzun, Lokman; Denizli, Adil (Elsevier Science BV, 2012)Hydrophobic interaction chromatography (HIC) is increasingly used for protein purification, separation and other biochemical applications. The aim of this study was to prepare hydrophobic microbeads and to investigate their ... -
Immunoglobulin G recognition with F-ab fragments imprinted monolithic cryogels: Evaluation of the effects of metal-ion assisted-coordination of template molecule
Aslıyüce, Sevgi; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2013)In this study, we applied the epitope imprinting approach to prepare molecularly imprinted monolithic cryogels for immunoglobulin G (IgG) recognition. In this respect, we imprinted F-ab fragments of IgG molecules instead ... -
Ion-imprinted supermacroporous cryogel, for in vitro removal of iron out of human plasma with beta thalassemia
Aslıyüce, Sevgi; Bereli, Nilay; Uzun, Lokman; Onur, Mehmet Ali; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2010)The aim of this study is to prepare an ion-imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-(L)-cysteine methyl ester) [PHEMAC] cryogel which can be used to remove Fe3+ ions from beta thalassemia patient plasma in ... -
L-Histidine imprinted supermacroporous cryogels for protein recognition
Bereli, Nilay; Saylan, Yeseren; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2011)Molecular imprinting is a method for making selective binding sites in synthetic polymers using a molecular template. The aim of this study is to prepare L-histidine-imprinted poly(hydroxy ethylmethacrylate) based ... -
Ligand exchange and MIP-based paraoxon memories onto QCM sensor
Özkütük, Ebru Birlik; Emir Diltemiz, Sibel; Özalp, Elif; Uzun, Lokman; Ersöz, Arzu (Springer, 2015)In this study, we have aimed to prepare quartz crystal microbalance (QCM) sensor using paraoxon-imprinted particles. Firstly, methacryloyl antipyrine (MAAP)-based metal-chelate-coordinated pre-complex has been prepared and ... -
Magnetic Nanoparticles for Plasmid DNA Purification through Hydrophobic Interaction Chromatography
Uzek, Recep; Özkara, Serpil; Gungunes, Hakan; Uzun, Lokman; Şenel, Serap (Taylor & Francis Inc, 2014)Magnetic poly(2-hydroxyethyl methacrylate-co-N-methacryloyl- L-phenyl alanine), p(HEMA-co-MAPA) nanoparticles were produced by emulsion polymerization technique. The nanoparticles were characterized by zetasizer, atomic ... -
Microcontact imprinted surface plasmon resonance biosensor for rapid procalcitonin detection
Şener, gülsu; Özgür, Erdoğan; Rad, Abbas Y.; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (American Chemical Society, 2013)… -
Molecular imprinting based composite cryogel membranes for purification of anti-hepatitis B surface antibody by fast protein liquid chromatography
Aslıyüce, Sevgi; Uzun, Lokman; Rad, Abbas Yousefi; Ünal, Serhat; Say, Rıdvan; Denizli, Adil (Elsevier Science BV, 2012)In the present study, we have focused our attention to prepare molecular imprinted composite cryogel membranes for purification of hepatitis B surface antibody (anti-HBs) by fast protein liquid chromatography. Before the ... -
Molecularly imprinted cryogel cartridges for the specific filtration and rapid separation of interferon alpha
Corman, Mehmet Emin; Armutcu, Canan; Özkara, Serpil; Uzun, Lokman; Denizli, Adil (Royal Soc Chemistry, 2015)In this study, we synthesised specific filtration cartridges with selective recognition sites for target molecules and used them to separate interferon alpha-2b from aqueous solutions. We combined molecular imprinting ... -
Multiclonal plastic antibodies for selective aflatoxin extraction from food samples
Bayram, Engin; Yılmaz, Erkut; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (Elsevier Sci LTD, 2017)Herein, we focused on developing a new generation of monolithic columns for extracting aflatoxin from real food samples by combining the superior features of molecularly imprinted polymers and cryogels. To accomplish this, ... -
A New Molecular Imprinting-Based Mass-Sensitive Sensor for Real-Time Detection of 17 beta-Estradiol from Aqueous Solution
Özgür, Erdoğan; Yılmaz, Erkut; Şener, gülsu; Uzun, Lokman; Say, Rıdvan; Denizli, Adil (Wiley, 2013)The 17-estradiol (E2), natural steroid hormone, is one of the most potent endocrine disrupting compounds even at ng L-1 levels. Its rapid, selective and sensitive detection is intensively required. In this study, quartz ...
