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Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models
Ak, Dilek; Kumar, Vijaya B.; Ryerse, Jan S.; Farr, Susan A.; Verma, Şulekha; Nonaka, Naoko; Banks, William A. (Sage Publications Inc, 2009)By isolating for the first time ever a peptide transporter from the blood-brain barrier (BBB) and developing an antisense that selectively targets the brain-to-blood efflux component, we were able to deliver a therapeutic ...
