Ara
Toplam kayıt 12, listelenen: 1-10
Synthesis and In vitro Evaluation of Thiadiazole Derivatives as AChE, BuChE and LOX Inhibitors
(Bentham Science Publ LTD, 2014)
N'-Benzylidene-2-[[5-(phenylamino)-1,3,4-thiadiazol-2-yl]thio]acetohydrazide derivatives (5a-p) were synthesized to screen for their AChE, BuChE and LOX inhibitory activity. The CCK-8 assay was also carried out to determine ...
Synthesis of some hydrazone derivatives bearing purine moiety as anticancer agents [Antikanser ajanlar olarak pürin parçasi{dotless} taşi{dotless}yan bazi{dotless} hidrazon türevlerinin sentezi]
(Turkish Pharmacists Association, 2014)
In the present study, some hydrazone derivatives were synthesized via the reaction of 6-hydrazino-9-(ß-D-ribofuranosyl)-9H-purine with various benzaldehydes. The structures of the compounds were elucidated by spectroscopic ...
Synthesis and Evaluation of Bis-pyrazoline Derivatives as Potential Antimicrobial Agents
(Bentham Science Publ LTD, 2014)
In the present study, 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazole-1-(4-arylthiazol-2-yl)] derivatives (3a-h) were obtained via the reaction of 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazo ...
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2014)
New pyrazole-based thiazolyl hydrazone derivatives were obtained via the ring closure reaction of 3,5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2-bromoacetophenone derivatives. The compounds were ...
Novel Naphthyridine-Hydrazone Derivatives and their Antimicrobial Activity
(2014)
Amaç: Bu çalışmada, on yeni Naftiridin-Hidrazon türevinin sentezi ve antimikrobiyal aktivitelerinin değerlendirilmesi amaçlanmıştır. Materyal ve Metod: Sentezlenen bileşiklerin yapıları 1H-NMR ve MS spectral verileri ile ...
Synthesis and Evaluation of Thiazole - Pyrimidine Derivatives as New Anticandidal and Cytotoxic Agents
(Springer, 2014)
The aim of this study was to describe the synthesis of four new 2-(3,4-diphenyl-3H-thiazol-2-ylidene)amino-4,6-dimethylpyrimidine derivatives, which were screened for their anticandidal activity and cytotoxicity. The title ...
Synthesis and antiproliferative activity of new 1,5-disubstituted tetrazoles bearing hydrazone moiety
(Springer Birkhauser, 2014)
A new class of tetrazole-hydrazone derivatives including chloro-substituted phenyl moiety were synthesized to perform anticancer activity screening. The structural elucidation of the compounds was performed by IR, H-1 NMR, ...
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
(MDPI AG, 2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ...
Synthesis and Antimicrobial Activity of New Pyrimidine-Hydrazones
(Bentham Science Publ LTD, 2014)
The synthesis of twelve new pyrimidine hydrazone derivatives and subsequent evaluation of their antimicrobial activities were the aims of this present work. The intermediate product 2-[(pyrimidin-2-yl)thio]acetohydrazide ...
Synthesis and In Vitro Evaluation of Some Hydrazone Derivatives as Potential Antibacterial Agents
(Bentham Science Publ LTD, 2014)
Nineteen N'-(benzylidene)-2-[(pyrimidin-2-yl)thio]acetohydrazides were obtained via the nucleophilic addition-elimination reaction of 2-[(pyrimidin-2-yl)thio)]acetohydrazide with aromatic aldehydes. The synthesized compounds ...